Results 51 to 60 of about 159,479 (261)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Seroprevalencia de la infección por Helicobacter pylori en pacientes con Gastritis Crónica, Úlcera Duodenal y Gástrica: Primer estudio de corte retrospectivo Seroprevalence of Helicobacter pylori infection in chronic gastritis patients, duodenal and gastric ulcer patients

Revista Cubana de Investigaciones Biomédicas, 2008
Objectivo. El objetivo de este estudio fue analizar la seroprevalencia de la población en tres centros hospitalarios, correspondientes a tres países; Venezuela, Cuba y República Dominicana. Métodos.
Beatriz Gutiérrez, María Eugenia Cavazza, Diana Ortiz, María Correnti, Teresita Vidal, Francis Mégraud, Manuel Guerram, Patricia Álvarez   +7 more
doaj  

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Helicobacter pylori virulence factors in duodenal ulceration: A primary cause or a secondary infection causing chronicity [PDF]

, 2006
Reports from countries with a high prevalence of Helicobacter pylori. (H pylori) infection do not show a proportionately high prevalence of duodenal ulceration, suggesting the possibility that H pylori cannot be a primary cause of duodenal ulceration. It
Hobsley, M, Tovey, FI, Holton, J
core  

Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8 [PDF]

, 2010
Farnbacher M, Jahns T, Willrodt D, et al. Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8. BMC Genomics.
Haas, Rainer, Rainer Haas, Farnbacher, Max, Rieder Gabriele, Goesmann, Alexander ; https://orcid.org/, Farnbacher Max, Kurtz, Stefan, Rieder, Gabriele, Kurtz Stefan, Gabriele Rieder, Alexander Goesmann, Rolf Daniel, Daniel, Rolf, Willrodt Dirk, Dirk Willrodt, Max Farnbacher, Jahns, Thomas, Goesmann Alexander, Haas Rainer, Goesmann, Alexander, Thomas Jahns, Stefan Kurtz, Daniel Rolf, Willrodt, Dirk, Jahns Thomas, Gabriele, Rieder   +25 more
core   +1 more source

Gastric Stem Cells: Physiological and Pathological Perspectives

Frontiers in Cell and Developmental Biology, 2020
Gastric epithelium operates in a hazardous environment that curtails the lifespan of the constituent cells, imposing a requirement for continuous epithelial renewal.
Shiyu Xiao, Shiyu Xiao, Liya Zhou, Liya Zhou   +3 more
doaj   +1 more source

Helicobacter pylori and the management of gastro-oesophageal reflux disease [PDF]

, 2005
This thesis is centred on the current controversy and possible links between H. pylori and GORD and whether the infection should be eradicated in those requiring long PPIs.
Raghunath, Anathakrishnapuram Srinivasan
core  

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

The mechanism of vitamin D3 in preventing colorectal cancer through network pharmacology

Frontiers in Pharmacology, 2023
Objective: Colorectal cancer (CRC) is a common cancer that cannot be detected at an early stage and is a major challenge in oncology research. Studies have shown that vitamin D3 has some anti-cancer and preventive effects on colorectal cancer, but the ...
Kang Rong, Kang Rong, Qingmin He, Qingmin He, Shu Chen, Yong Yu, Yong Yu, Lu Mei, Lu Mei, Yang Mi, Yang Mi, Liufan Mu, Liufan Mu, Mingyang Zhu, Mingyang Zhu, Mengjiao Nan, Mengjiao Nan, Xiaoyang Zhang, Xiaoyang Zhang, Zhaoyang Wan, Zhaoyang Wan, Huang Huang, Huang Huang, Pengyuan Zheng, Pengyuan Zheng   +24 more
doaj   +1 more source