Results 11 to 20 of about 97,542 (214)

Functional maps of neocortical local circuitry

open access: yesFrontiers in Neuroscience, 2007
This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
doaj   +1 more source

A Simulation Study on the Effects of Dendritic Morphology on Layer V Prefontal Pyramidal Cell Firing Behavior

open access: yesFrontiers in Cellular Neuroscience, 2014
Pyramidal cells, the most abundant neurons in neocortex, exhibit significant structural variability across different brain areas and layers in different species.
Maria ePsarrou   +9 more
doaj   +1 more source

Non-Hebbian Spike-Timing Dependent Plasticity in Cerebellar Circuits

open access: yesFrontiers in Neural Circuits, 2013
Spike-timing dependent plasticity (STDP) provides a cellular implementation of the Hebb postulate, which states that synapses, whose activity repeatedly drives action potential firing in target cells, are potentiated.
Claire ePiochon   +3 more
doaj   +1 more source

Juvenile Social Isolation Enhances the Activity of Inhibitory Neuronal Circuits in the Medial Prefrontal Cortex

open access: yesFrontiers in Cellular Neuroscience, 2020
During brain development, the design of primary neural networks is primarily determined by environmental stimuli after their formation. In particular, the juvenile period is critical, during which neuronal circuits that consist of both excitatory and ...
Kazuhiko Yamamuro   +7 more
doaj   +1 more source

D1- and D2-type dopamine receptors are immunolocalized in pial and layer I astrocytes in the rat cerebral cortex

open access: yesFrontiers in Neuroanatomy, 2023
Pial astrocytes, a cellular component of the cerebral cortex surface structure, are observed in a wide range of mammalian species. Despite being recognized as such, the functional potential of pial astrocytes has long been overlooked.
Satoko Oda   +2 more
doaj   +1 more source

Sub-millisecond firing synchrony of closely neighboring pyramidal neurons in hippocampal CA1 of rats during delayed non-matching to sample task

open access: yesFrontiers in Neural Circuits, 2009
Firing synchrony among neurons is thought to play functional roles in several brain regions. In theoretical analyses, firing synchrony among neurons within sub-millisecond precision is feasible to convey information.
Susumu Takahashi   +3 more
doaj   +1 more source

Chemogenetic Silencing of Differentiating Cortical Neurons Impairs Dendritic and Axonal Growth

open access: yesFrontiers in Cellular Neuroscience, 2022
Electrical activity is considered a key driver for the neurochemical and morphological maturation of neurons and the formation of neuronal networks. Designer receptors exclusively activated by designer drugs (DREADDs) are tools for controlling neuronal ...
Ina Gasterstädt   +8 more
doaj   +1 more source

The Diversity of Cortical Inhibitory Synapses

open access: yesFrontiers in Neural Circuits, 2016
The most typical and well known inhibitory action in the cortical microcircuit is a strong inhibition on the target neuron by axo-somatic synapses. However, it has become clear that synaptic inhibition in the cortex is much more diverse and complicated ...
Yoshiyuki eKubota   +8 more
doaj   +1 more source

Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity

open access: yeseLife, 2021
Glucose is the mandatory fuel for the brain, yet the relative contribution of glucose and lactate for neuronal energy metabolism is unclear. We found that increased lactate, but not glucose concentration, enhances the spiking activity of neurons of the ...
Anastassios Karagiannis   +17 more
doaj   +1 more source

Optogenetic inhibition-mediated activity-dependent modification of CA1 pyramidal-interneuron connections during behavior

open access: yeseLife, 2020
In vitro work revealed that excitatory synaptic inputs to hippocampal inhibitory interneurons could undergo Hebbian, associative, or non-associative plasticity.
Igor Gridchyn   +3 more
doaj   +1 more source

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