Results 1 to 10 of about 12,133,346 (298)
Pyramidal Cells in Olfactory Cortex. [PDF]
Chem Senses, 2021 The neocortex and olfactory cortices share many features including their laminar organization, developmental sequences, and cell types. Previous work indicates that neocortical pyramidal cells exhibit a gradient of dendritic size: cells involved in the ...
Brunjes PC.
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Cell-type specific innervation of cortical pyramidal cells at their apical dendrites
eLife, 2020 We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi +4 more
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Definitions, 2020 A neuron located in the cerebral cortex, hippocampus, and amygdala that is characterized by a pyramidal-shaped cell body and apical and basal dendritic trees. Pyramidal cells are involved in complex cortical functions.
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Parvalbumin-positive basket cells differentiate among hippocampal pyramidal cells. [PDF]
Neuron, 2014 CA1 pyramidal cells (PCs) are not homogeneous but rather can be grouped by molecular, morphological, and functional properties. However, less is known about synaptic sources differentiating PCs. Using paired recordings in vitro, two-photon Ca(2+) imaging in vivo, and computational modeling, we found that parvalbumin-expressing basket cells (PVBCs ...
Sang-Hun Lee +7 more
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Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections [PDF]
Frontiers in Cellular NeuroscienceBackgroundSocial experience during development is crucial for the functional maturation of the prefrontal cortex (PFC). Juvenile social isolation (JSI) causes severe PFC dysfunction. JSI reduces intrinsic excitability and excitatory synaptic inputs for a
Yosuke Nishihata +11 more
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Pyramidal cells accumulate chloride at seizure onset. [PDF]
Neurobiology of Disease, 2012 Seizures are thought to originate from a failure of inhibition to quell hyperactive neural circuits, but the nature of this failure remains unknown. Here we combine high-speed two-photon imaging with electrophysiological recordings to directly evaluate the interaction between populations of interneurons and principal cells during the onset of seizure ...
K. Lillis +4 more
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Layer III pyramidal cells in the prefrontal cortex reveal morphological changes in subjects with depression, schizophrenia, and suicide [PDF]
Translational Psychiatry, 2022 Brodmann Area 46 (BA46) has long been regarded as a hotspot of disease pathology in individuals with schizophrenia (SCH) and major depressive disorder (MDD).
Nick Y. Larsen +9 more
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Objective Morphological Classification of Neocortical Pyramidal Cells
Cerebral Cortex, 2019 A consensus on the number of morphologically different types of pyramidal cells (PCs) in the neocortex has not yet been reached, despite over a century of anatomical studies, due to the lack of agreement on the subjective classifications of neuron types,
Lida Kanari +9 more
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Autapses enhance bursting and coincidence detection in neocortical pyramidal cells
Nature Communications, 2018 While autapses are synapses made by a neuron onto itself, its functional significance in pyramidal cells are not clear. Here, the authors show that in the mammalian neocortex, autapses of pyramidal cells can enhance burst firing and coincidence detection
Luping Yin +12 more
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Cell-type specific inhibitory plasticity in subicular pyramidal cells. [PDF]
Front Cell NeurosciThe balance between excitation and inhibition is essential to the proper function of cortical circuits. To maintain this balance during dynamic network activity, modulation of the strength of inhibitory synapses is a central requirement. In this study, we aimed to characterize perisomatic inhibition and its plasticity onto pyramidal cells (PCs) in the ...
Guinet A +4 more
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