Results 11 to 20 of about 12,133,346 (298)

Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells. [PDF]

open access: yesNeuron, 2007
Reliable activation of inhibitory pathways is essential for maintaining the balance between excitation and inhibition during cortical activity. Little is known, however, about the activation of these pathways at the level of the local neocortical microcircuit. We report a disynaptic inhibitory pathway among neocortical pyramidal cells (PCs). Inhibitory
G. Silberberg, H. Markram
semanticscholar   +3 more sources

Hippocampal pyramidal cells: the reemergence of cortical lamination [PDF]

open access: yesBrain Structure and Function, 2011
The increasing resolution of tract-tracing studies has led to the definition of segments along the transverse axis of the hippocampal pyramidal cell layer, which may represent functionally defined elements.
L. Slomianka   +4 more
semanticscholar   +6 more sources

Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells. [PDF]

open access: yesPLoS Computational Biology, 2022
Dendrites of cortical pyramidal cells are densely populated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, a.k.a. Ih channels. Ih channels are targeted by multiple neuromodulatory pathways, and thus are one of the key ion-channel ...
Tuomo Mäki-Marttunen   +1 more
doaj   +2 more sources

All active hippocampal pyramidal cells are place cells. [PDF]

open access: yesiScience
Hippocampal place cells – neurons whose activity is modulated by spatial position – are considered an essential substrate of spatial cognition. Despite decades of research, the fraction of hippocampal place cells remains debated, with studies reporting between 20% and 90% of the recorded populations. This raises the question of whether distinct subsets
Talpir I, Sheintuch L, Rubin A, Ziv Y.
europepmc   +2 more sources

Change of Nurr1 expression in mouse hippocampal CA3 region following excitotoxic neuronal damage [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Nuclear receptor-related protein 1 (Nurr1), one of immediate-early genes, is a member of orphan nuclear receptor family. The aim of this study was to investigate the time-dependent change of Nurr1 protein expression in the mouse hippocampal
Choong-Hyun Lee
doaj   +1 more source

The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain

open access: yesMolecular Brain, 2022
Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain.
Da-Yu Zhu   +9 more
doaj   +1 more source

Age-related changes in the human primary motor cortex: A macroscopic and microscopic study

open access: yesAsian Journal of Medical Sciences, 2021
Background: Cerebral hemisphere has outer gray matter and inner white matter. The cerebrum is folded into gyri and sulci in order to accommodate it in the skull. The thickness of the gray matter varies at sulci and gyri and the mean thickness may be from
Anne George , Usha K K
doaj   +1 more source

Drugs of Abuse Differentially Alter the Neuronal Excitability of Prefrontal Layer V Pyramidal Cell Subtypes

open access: yesFrontiers in Cellular Neuroscience, 2021
The medial prefrontal cortex (mPFC) plays an important role in regulating executive functions including reward seeking, task flexibility, and compulsivity.
Jonna M. Leyrer-Jackson   +2 more
doaj   +1 more source

Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

open access: yesJournal of Biological Research, 2023
Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi   +5 more
doaj   +1 more source

Subliminal messages in hippocampal pyramidal cells [PDF]

open access: yesThe Journal of Physiology, 2002
Synaptic activity regulates gene transcription in neurons. The coupling between synaptic transmission and transcription is accomplished by the second messenger calcium, which enters the cell through synaptic receptors and voltage-gated calcium channels and binds enzymes that activate transcription factors.
Thomas G, Oertner, Karel, Svoboda
openaire   +2 more sources

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