Results 11 to 20 of about 12,133,346 (298)
Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells. [PDF]
Reliable activation of inhibitory pathways is essential for maintaining the balance between excitation and inhibition during cortical activity. Little is known, however, about the activation of these pathways at the level of the local neocortical microcircuit. We report a disynaptic inhibitory pathway among neocortical pyramidal cells (PCs). Inhibitory
G. Silberberg, H. Markram
semanticscholar +3 more sources
Hippocampal pyramidal cells: the reemergence of cortical lamination [PDF]
The increasing resolution of tract-tracing studies has led to the definition of segments along the transverse axis of the hippocampal pyramidal cell layer, which may represent functionally defined elements.
L. Slomianka +4 more
semanticscholar +6 more sources
Excitatory and inhibitory effects of HCN channel modulation on excitability of layer V pyramidal cells. [PDF]
Dendrites of cortical pyramidal cells are densely populated by hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, a.k.a. Ih channels. Ih channels are targeted by multiple neuromodulatory pathways, and thus are one of the key ion-channel ...
Tuomo Mäki-Marttunen +1 more
doaj +2 more sources
All active hippocampal pyramidal cells are place cells. [PDF]
Hippocampal place cells – neurons whose activity is modulated by spatial position – are considered an essential substrate of spatial cognition. Despite decades of research, the fraction of hippocampal place cells remains debated, with studies reporting between 20% and 90% of the recorded populations. This raises the question of whether distinct subsets
Talpir I, Sheintuch L, Rubin A, Ziv Y.
europepmc +2 more sources
Change of Nurr1 expression in mouse hippocampal CA3 region following excitotoxic neuronal damage [PDF]
Objective(s): Nuclear receptor-related protein 1 (Nurr1), one of immediate-early genes, is a member of orphan nuclear receptor family. The aim of this study was to investigate the time-dependent change of Nurr1 protein expression in the mouse hippocampal
Choong-Hyun Lee
doaj +1 more source
Chronic pain damages the balance between excitation and inhibition in the sensory cortex. It has been confirmed that the activity of cortical glutamatergic pyramidal cells increases after chronic pain.
Da-Yu Zhu +9 more
doaj +1 more source
Age-related changes in the human primary motor cortex: A macroscopic and microscopic study
Background: Cerebral hemisphere has outer gray matter and inner white matter. The cerebrum is folded into gyri and sulci in order to accommodate it in the skull. The thickness of the gray matter varies at sulci and gyri and the mean thickness may be from
Anne George , Usha K K
doaj +1 more source
The medial prefrontal cortex (mPFC) plays an important role in regulating executive functions including reward seeking, task flexibility, and compulsivity.
Jonna M. Leyrer-Jackson +2 more
doaj +1 more source
Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi +5 more
doaj +1 more source
Subliminal messages in hippocampal pyramidal cells [PDF]
Synaptic activity regulates gene transcription in neurons. The coupling between synaptic transmission and transcription is accomplished by the second messenger calcium, which enters the cell through synaptic receptors and voltage-gated calcium channels and binds enzymes that activate transcription factors.
Thomas G, Oertner, Karel, Svoboda
openaire +2 more sources

