Results 21 to 30 of about 12,133,346 (298)
Dopamine action on hippocampal pyramidal cells [PDF]
The Journal of Neuroscience, 1982 Dopamine (DA) was applied to CA1 region pyramidal cells in slices of guinea pig hippocampus maintained in vitro in order to examine its electrophysiological effect on CNS neurons. DA induced hyperpolarization of membrane potential and an increased conductance in 75% the 21 CA1 neurons to which it was applied.
L S, Benardo, D A, Prince
openaire +2 more sources
Biology Open, 2022 Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in neurons in the central nervous system. It has been documented that HCN channels regulate the intrinsic excitability of pyramidal cells in the medial prefrontal ...
Wei Cai +3 more
doaj +1 more source
Expression of Brain Derived Growth Factor in Hippocampus of Mid Gestational Human Fetuses [PDF]
Journal of Clinical and Diagnostic Research, 2020 Introduction: Brain Derived Growth Factor (BDNF) is a sub member of neurotrophin family and is a critical regulator of formation and plasticity of neuronal networks in hippocampal formation.
Shilpi Garg, Sabita Mishra, Swati Tiwari
doaj +1 more source
Recurrent connections between CA2 pyramidal cells [PDF]
Hippocampus, 2018 AbstractRecurrent excitatory synapses are shown theoretically to play roles in memory storage and associative learning, and such recurrent synapses are well described to occur in the CA3 region of the hippocampus. Here, we report that the CA2 region also contains recurrent excitatory monosynaptic couplings.
Okamoto, Kazuki, Ikegaya, Yuji
openaire +2 more sources
Frontiers in Neuroanatomy, 2014 Pyramidal cells are characterised by markedly different sized dendritic trees, branching patterns and spine density across the cortical mantle. Moreover, pyramidal cells have been shown to differ in structure among homologous cortical areas in different ...
Guy eElston, Paul eManger
doaj +1 more source
Neuroprotective effect of water lily (Nymphaea pubescens Willd) seed ethanolic extract against trimethyltin-induced cognitive impairment and neurodegeneration in mice [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Cognitive impairments are profound outcomes of neurodegenerative disease, a global health issue. Water lily (Nymphaea pubescens, Nymphaeaceae) extracts have been reported to counteract oxidative stress.
Dinda Fadhilah Belahusna +2 more
doaj +1 more source
Nature Communications, 2018 Astrocytes are important regulators of excitatory synaptic networks. However, astrocytes regulation of inhibitory synaptic systems remains ill defined. This is particularly relevant since GABAergic interneurons regulate the activity of excitatory cells ...
Marco Matos +8 more
semanticscholar +1 more source
Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics
Molecular Brain, 2012 Background The medial prefrontal cortex (mPFC) serves major executive functions. mPFC output to subcortical brain areas such as the amygdala controls emotional processing and plays an important role in fear extinction.
Ji Guangchen, Neugebauer Volker
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 The acid sphingomyelinase (ASM) converts sphingomyelin into ceramide. Recent work has advanced the ASM/ceramide system as a major player in the pathogenesis of major depressive disorder (MDD).
Chih-Hung Lin +4 more
doaj +1 more source
Distinct roles of SOM and VIP interneurons during cortical Up states
Frontiers in Neural Circuits, 2016 During cortical network activity, recurrent synaptic excitation among pyramidal neurons is approximately balanced by synaptic inhibition, which is provided by a vast diversity of inhibitory interneurons.
Garrett T. Neske +2 more
doaj +1 more source