Results 31 to 40 of about 12,133,346 (298)

Recurrent synapses and circuits in the CA3 region of the hippocampus: an associative network.

Frontiers in Cellular Neuroscience, 2014
In the CA3 region of the hippocampus, pyramidal cells excite other pyramidal cells and interneurons. The axons of CA3 pyramidal cells spread throughout most of the region to form an associative network.
Richard eMiles, Caroline eLe Duigou, Jean eSimonnet, Maria eTelenczuk, Desdemona eFricker   +4 more
doaj   +1 more source

A simulation study on the effects of dendritic morphology on layer V PFC pyramidal cell firing behavior

Frontiers in Systems Neuroscience, 2014
The majority of neuronal cells found in the cerebral cortex are pyramidal neurons. Their function has been associated with higher cognitive and emotional functions. Pyramidal neurons have a characteristic structure, consisting of a triangular shaped soma
Maria Psarrou, Maria Psarrou, Maria Psarrou, Alexandra Tzilivaki   +3 more
doaj   +1 more source

Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood

Journal of Neuroscience, 1990
Gonadal steroids are known to influence hippocampal physiology in adulthood. It is presently unknown whether gonadal steroids influence the morphology of hippocampal neurons in the adult intact rat brain. In order to determine whether female sex hormones
E. Gould, C. Woolley, M. Frankfurt, B. McEwen   +3 more
semanticscholar   +1 more source

Three axonal projection routes of individual pyramidal cells in the ventral CA1 hippocampus

Frontiers in Neuroanatomy, 2014
Pyramidal cells of the ventral hippocampal CA1 area have numerous and diverse distant projections to other brain regions including the temporal and parietal association areas, visual, auditory, olfactory, somatosensory, gustatory, and visceral areas, and
Antónia Arszovszki, Zsolt Borhegyi, T. Klausberger   +2 more
semanticscholar   +1 more source

Interaction of Norepinephrine and Glucocorticoids Modulate Inhibition of Principle Cells of Layer II Medial Entorhinal Cortex in Male Mice

Frontiers in Synaptic Neuroscience, 2018
Spatial memory processing requires functional interaction between the hippocampus and the medial entorhinal cortex (MEC). The grid cells of the MEC are most abundant in layer II and rely on a complex network of local inhibitory interneurons to generate ...
Jeremiah P. Hartner, Laura A. Schrader, Laura A. Schrader   +2 more
doaj   +1 more source

The contribution of synaptic location to inhibitory gain control in pyramidal cells

Physiological Reports, 2013
The activity of pyramidal cells is controlled by two opposing forces: synaptic inhibition and synaptic excitation. Interestingly, these synaptic inputs are not distributed evenly across the dendritic trees of cortical pyramidal cells. Excitatory synapses
F. Pouille, Oliver Watkinson, M. Scanziani, A. Trevelyan   +3 more
semanticscholar   +1 more source

Ventromedial Prefrontal Cortex Pyramidal Cells Have a Temporal Dynamic Role in Recall and Extinction of Cocaine-Associated Memory

Journal of Neuroscience, 2013
In addicts, associative memories related to the rewarding effects of drugs of abuse can evoke powerful craving and drug seeking urges, but effective treatment to suppress these memories is not available.
Michel C. van den Oever, D. Rotaru, Jasper A. Heinsbroek, Y. Gouwenberg, K. Deisseroth, G. Stuber, H. Mansvelder, A. Smit   +7 more
semanticscholar   +1 more source

Overexpression of Calretinin Enhances Short-Term Synaptic Depression

Frontiers in Cellular Neuroscience, 2019
Analysis of the effects of various proteins on short-term synaptic plasticity is a difficult task, which may require the use of knockout animals. Here, we propose an alternative experimental approach for studying the roles of desired proteins in synaptic
Alexey P. Bolshakov, Alexey P. Bolshakov, Alexander Kolleker, Alexander Kolleker, Evgenia P. Volkova, Fliza Valiullina-Rakhmatullina, Peter M. Kolosov, Andrei Rozov, Andrei Rozov   +8 more
doaj   +1 more source

Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

Journal of Neuroscience, 1989
Serial electron microscopy and 3-D reconstructions of dendritic spines from hippocampal area CA 1 dendrites were obtained to evaluate 2 questions about relationships between spine geometry and synaptic efficacy.
KM Harris, J. Stevens
semanticscholar   +1 more source

Long-term potentiation at pyramidal cell to somatostatin interneuron synapses controls hippocampal network plasticity and memory

iScience, 2022
Summary: Hippocampal somatostatin (SOM) cells are dendrite-projecting inhibitory interneurons. CA1 SOM cells receive major excitatory inputs from pyramidal cells (PC-SOM synapses) which show mGluR1a- and mTORC1-mediated long-term potentiation (LTP).
Azam Asgarihafshejani, Ève Honoré, François-Xavier Michon, Isabel Laplante, Jean-Claude Lacaille   +4 more
doaj   +1 more source