Results 41 to 50 of about 267,739 (297)

A universal model for spike-frequency adaptation [PDF]

open access: yes, 2003
Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation.
Andreas V. M. Herz   +3 more
core   +1 more source

Pyramidal cells in prefrontal cortex: comparative observations reveal unparalleled specializations in neuronal structure among primate species.

open access: yesFrontiers in Neuroanatomy, 2011
The most ubiquitous neuron in the cerebral cortex, the pyramidal cell, is characterised by markedly different dendritic structure among different cortical areas. The complex pyramidal cell phenotype in granular prefrontal cortex (gPFC) of higher primates
Guy eElston   +4 more
doaj   +1 more source

GluN2B-NMDAR subunit contribution on synaptic plasticity: A phenomenological model for CA3-CA1 synapses

open access: yesFrontiers in Synaptic Neuroscience, 2023
Synaptic plasticity is believed to be a key mechanism underlying learning and memory. We developed a phenomenological N-methyl-D-aspartate (NMDA) receptor-based voltage-dependent synaptic plasticity model for synaptic modifications at hippocampal CA3-CA1
Justinas J. Dainauskas   +4 more
doaj   +1 more source

Neuroscience Jokes. Pyramidal Neurons

open access: yes, 2023
Short book with educative jokes, to make us think and remember aspects of pyramidal function and connectivity we still dont fully understand.
delgado ruz, isabel, chadderton, Paul
openaire   +1 more source

Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]

open access: yes, 2013
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
core   +1 more source

NPTX2 and cognitive dysfunction in Alzheimer’s Disease

open access: yeseLife, 2017
Memory loss in Alzheimer’s disease (AD) is attributed to pervasive weakening and loss of synapses. Here, we present findings supporting a special role for excitatory synapses connecting pyramidal neurons of the hippocampus and cortex with fast-spiking ...
Mei-Fang Xiao   +19 more
doaj   +1 more source

Double trouble? Potential for hyperexcitability following both channelopathic up- and downregulation of Ih in epilepsy

open access: yesFrontiers in Neuroscience, 2009
Studies of pathological ion channel regulation as an underlying mechanism of epilepsy have revealed alterations of the h-current in several animal models.
Jonas Dyhrfjeld-Johnsen   +3 more
doaj   +1 more source

Inhibitory control of site-specific synaptic plasticity in a model CA1 pyramidal neuron

open access: yes, 2015
A computational model of a biochemical network underlying synaptic plasticity is combined with simulated on-going electrical activity in a model of a hippocampal pyramidal neuron to study the impact of synapse location and inhibition on synaptic ...
Graham, Bruce, Saudargiene, Ausra
core   +1 more source

Branch-specific plasticity enables self-organization of nonlinear computation in single neurons [PDF]

open access: yes, 2011
It has been conjectured that nonlinear processing in dendritic branches endows individual neurons with the capability to perform complex computational operations that are needed in order to solve for example the binding problem.
Maass, Wolfgang, Legenstein, Robert
core   +1 more source

Dynamical Mean Field approximation of a canonical cortical model for studying inter-population synchrony [PDF]

open access: yes, 2011
The goal of this paper is twofold. We propose and explore a model to study the synchronization among populations in the canonical model of the neocortex proposed previously by (R.J. Douglas, K.A.C. Martin, A functional microcircuit for cat visual cortex.
Roberto Carlos Sotero Diaz   +2 more
core   +1 more source

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