Results 21 to 30 of about 267,739 (297)

Size of hippocampal pyramidal neurons in schizophrenia [PDF]

British Journal of Psychiatry, 2003
BackgroundMeta-analyses of hippocampal size have indicated that this structure is smaller in schizophrenia. This could reflect a reduction in the size of constituent neurons or a reduced number of neurons.AimsTo measure the size of hippocampal pyramidal neurons in the brains of people with and without schizophrenia.MethodPyramidal neuron size in ...
Highley, JR, Walker, M, McDonald, B, Crow, T, Esiri, M   +4 more
openaire   +4 more sources

The dendritic density field of a cortical pyramidal cell [PDF]

, 2012
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail.
Hermann Cuntz, Cuntz, H. ; https://orcid.org/, Cuntz, Hermann, Hermann eCuntz   +3 more
core   +1 more source

Identification of Synaptic Integration Mode in CA3 Pyramidal Neuron Model

, 2019
International audienceA morphologically realistic and anisotropic model of CA3 pyramidal neuron was developed to determine the synaptic integration modes the neuron is able to perform.
Jhunlyn Lorenzo, Sabir Jacquir, Lorenzo, Jhunlyn, Vuillaume, Roman, Jacquir, Sabir, Roman Vuillaume, Steephane Binczak, Binczak, Stéphane   +7 more
core   +4 more sources

Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta

iScience, 2020
Summary: Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impairment.
Sara Hijazi, Tim S. Heistek, Rolinka van der Loo, Huibert D. Mansvelder, August B. Smit, Ronald E. van Kesteren   +5 more
doaj   +1 more source

Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model

Neurobiology of Disease, 2023
Tau protein pathology is a hallmark of many neurodegenerative diseases, including Alzheimer's Disease or frontotemporal dementia. Synaptic dysfunction and abnormal visual evoked potentials have been reported in murine models of tauopathy, but little is ...
Aleksandra Parka, Caroline Degel, Jakob Dreyer, Ulrike Richter, Benjamin Hall, Jesper F. Bastlund, Bettina Laursen, Maiken Nedergaard, Florence Sotty, Paolo Botta   +9 more
doaj   +1 more source

Extracting non-linear integrate-and-fire models from experimental data using dynamic I–V curves [PDF]

, 2008
The dynamic I–V curve method was recently introduced for the efficient experimental generation of reduced neuron models. The method extracts the response properties of a neuron while it is subject to a naturalistic stimulus that mimics in vivo-like ...
Wulfram Gerstner, Richardson, Magnus J. E., Badel, Laurent, Berger, Thomas K., Sandrine Lefort, Lefort, Sandrine, Thomas K. Berger, Laurent Badel, Magnus J. E. Richardson, Petersen, Carl C. H., Gerstner, Wulfram, Carl C. H. Petersen, Richardson MJ, Badel L, Lefort S, Berger TK, Gerstner W, Petersen CC   +17 more
core   +2 more sources

Parameters used in a pyramidal neuron model with two excitatory conductances.

, 2023
Parameters used in a pyramidal neuron model with two excitatory conductances.
Julio C. Hechavarria (9624013), Johannes Wetekam (14660546), Michael Pasek (14660549), Luciana López-Jury (8601540), Francisco García-Rosales (8599803), Eugenia González-Palomares (8601543)   +5 more
core   +1 more source

Characterization of intracortical synaptic connections in the mouse anterior cingulate cortex using dual patch clamp recording

Molecular Brain, 2009
Summary The anterior cingulate cortex (ACC) is involved in sensory, cognitive, and executive functions. Studies of synaptic transmission and plasticity in the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions ...
Wu Long-Jun, Li Xiangyao, Chen Tao, Ren Ming, Zhuo Min   +4 more
doaj   +1 more source

Weak electric fields promote resonance in neuronal spiking activity: Analytical results from two-compartment cell and network models. [PDF]

PLoS Computational Biology, 2019
Transcranial brain stimulation and evidence of ephaptic coupling have sparked strong interests in understanding the effects of weak electric fields on the dynamics of neuronal populations. While their influence on the subthreshold membrane voltage can be
Josef Ladenbauer, Klaus Obermayer
doaj   +1 more source

Biophysics of Extracellular Action Potentials [PDF]

, 2007
The goal of this thesis is to analyze the generation of single unit extracellular action potentials (EAPs), and to explore pertinent issues in the interpretation of EAP recordings.
Gold, Carl
core   +1 more source