Results 21 to 30 of about 63,189 (307)
Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta
iScience, 2020 Summary: Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impairment.
Sara Hijazi +5 more
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Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model
Neurobiology of Disease, 2023 Tau protein pathology is a hallmark of many neurodegenerative diseases, including Alzheimer's Disease or frontotemporal dementia. Synaptic dysfunction and abnormal visual evoked potentials have been reported in murine models of tauopathy, but little is ...
Aleksandra Parka +9 more
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Molecular Brain, 2009 Summary The anterior cingulate cortex (ACC) is involved in sensory, cognitive, and executive functions. Studies of synaptic transmission and plasticity in the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions ...
Wu Long-Jun +4 more
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Weak electric fields promote resonance in neuronal spiking activity: Analytical results from two-compartment cell and network models. [PDF]
PLoS Computational Biology, 2019 Transcranial brain stimulation and evidence of ephaptic coupling have sparked strong interests in understanding the effects of weak electric fields on the dynamics of neuronal populations. While their influence on the subthreshold membrane voltage can be
Josef Ladenbauer, Klaus Obermayer
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Biophysics of Extracellular Action Potentials [PDF]
, 2007 The goal of this thesis is to analyze the generation of single unit extracellular action potentials (EAPs), and to explore pertinent issues in the interpretation of EAP recordings.
Gold, Carl
core +1 more source
Frontiers in Neuroanatomy, 2016 This work presents PyramidalExplorer, a new tool to interactively explore and reveal the detailed organization of the microanatomy of pyramidal neurons with functionally related models. It consists of a set of functionalities that allow possible regional
Pablo eToharia +15 more
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Frontiers in Neuroanatomy, 2020 Cognitive functions such as attention and working memory are modulated by noradrenaline receptors in the prefrontal cortex (PFC). The frontal eye field (FEF) has been shown to play an important role in visual spatial attention.
Max Lee +3 more
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Nrg1 Reverse Signaling in Cortical Pyramidal Neurons [PDF]
The Journal of Neuroscience, 2010 Peer ...
Peregrin, Sandra, Fazzari, Pietro
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The enigmatic function of chandelier cells
Frontiers in Neuroscience, 2010 Chandelier (or axo-axonic) cells are one of the most distinctive GABAergic interneurons in the brain. Their exquisite target specificity for the axon initial segment of pyramidal neurons, together with their GABAergic nature, long suggested the ...
Alan R Woodruff +2 more
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A realistic computational model for the formation of a Place Cell
Scientific Reports, 2023 Hippocampal Place Cells (PCs) are pyramidal neurons showing spatially localized firing when an animal gets into a specific area within an environment. Because of their obvious and clear relation with specific cognitive functions, Place Cells operations ...
Camille Mazzara, Michele Migliore
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