Results 31 to 40 of about 63,189 (307)

Classification of Cortical Neurons by Spike Shape and the Identification of Pyramidal Neurons

open access: yesCerebral Cortex, 2021
Abstract Many investigators who make extracellular recordings from populations of cortical neurons are now using spike shape parameters, and particularly spike duration, as a means of classifying different neuronal sub-types. Because of the nature of the experimental approach, particularly that involving nonhuman primates, it is very ...
Lemon RN, Baker SN, Kraskov A
openaire   +3 more sources

Extracting non-linear integrate-and-fire models from experimental data using dynamic I–V curves [PDF]

open access: yes, 2008
The dynamic I–V curve method was recently introduced for the efficient experimental generation of reduced neuron models. The method extracts the response properties of a neuron while it is subject to a naturalistic stimulus that mimics in vivo-like ...
Wulfram Gerstner   +11 more
core   +1 more source

Computational capacity of pyramidal neurons in the cerebral cortex [PDF]

open access: yesBrain Research, 2020
The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the underlying functional specializations, for input or output of neural information, respectively.
Georgiev, Danko D.   +3 more
openaire   +3 more sources

Postnatal development of dendritic calcium signaling in rat hippocampal pyramidal cells [PDF]

open access: yes, 2013
In CA1 pyramidal neurons, dendritic calcium transients in stratum radiatum were evoked in acute slices via backpropagating action potentials using patch clamp recordings.
Pohle, Jörg
core   +1 more source

Branch-specific plasticity enables self-organization of nonlinear computation in single neurons [PDF]

open access: yes, 2011
It has been conjectured that nonlinear processing in dendritic branches endows individual neurons with the capability to perform complex computational operations that are needed in order to solve for example the binding problem.
Maass, Wolfgang, Legenstein, Robert
core   +1 more source

Pyramidal cells in prefrontal cortex: comparative observations reveal unparalleled specializations in neuronal structure among primate species.

open access: yesFrontiers in Neuroanatomy, 2011
The most ubiquitous neuron in the cerebral cortex, the pyramidal cell, is characterised by markedly different dendritic structure among different cortical areas. The complex pyramidal cell phenotype in granular prefrontal cortex (gPFC) of higher primates
Guy eElston   +4 more
doaj   +1 more source

GluN2B-NMDAR subunit contribution on synaptic plasticity: A phenomenological model for CA3-CA1 synapses

open access: yesFrontiers in Synaptic Neuroscience, 2023
Synaptic plasticity is believed to be a key mechanism underlying learning and memory. We developed a phenomenological N-methyl-D-aspartate (NMDA) receptor-based voltage-dependent synaptic plasticity model for synaptic modifications at hippocampal CA3-CA1
Justinas J. Dainauskas   +4 more
doaj   +1 more source

A universal model for spike-frequency adaptation [PDF]

open access: yes, 2003
Spike-frequency adaptation is a prominent feature of neural dynamics. Among other mechanisms, various ionic currents modulating spike generation cause this type of neural adaptation.
Andreas V. M. Herz   +3 more
core   +1 more source

General Anesthesia Decouples Cortical Pyramidal Neurons [PDF]

open access: yesCell, 2020
The mystery of general anesthesia is that it specifically suppresses consciousness by disrupting feedback signaling in the brain, even when feedforward signaling and basic neuronal function are left relatively unchanged. The mechanism for such selectiveness is unknown.
Mototaka, Suzuki, Matthew E, Larkum
openaire   +2 more sources

The influence of GABAergic signaling on dendritic processing [PDF]

open access: yes, 2013
GABAergic (?-aminobutyric acid-releasing) signaling plays a crucial role in integration processes of pyramidal neurons. Specific subtypes of GABA releasing interneurons innervate different compartments of pyramidal neurons; thereby modulating the ...
Willadt, Silvia
core   +1 more source

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