Results 11 to 20 of about 63,189 (307)

Pyramidal neuron subtype diversity governs microglia states in the neocortex. [PDF]

open access: yesNature, 2022
Microglia are macrophages of the brain parenchyma that exist in multiple transcriptional states and reside within a wide range of neuronal environments. However, it is poorly understood how and where these states are generated.
Stogsdill JA   +5 more
europepmc   +2 more sources

Multiple synaptic connections into a single cortical pyramidal cell or interneuron in the anterior cingulate cortex of adult mice

open access: yesMolecular Brain, 2021
The ACC is an important brain area for the processing of pain-related information. Studies of synaptic connections within the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions such as pain, emotion and related ...
Jung-Hyun Alex Lee   +4 more
doaj   +1 more source

Cholinergic Inhibition of Neocortical Pyramidal Neurons [PDF]

open access: yesThe Journal of Neuroscience, 2005
Acetylcholine (ACh) is a central neurotransmitter critical for normal cognitive function. Here we show that transient muscarinic acetylcholine receptor activation directly inhibits neocortical layer 5 pyramidal neurons. Using whole-cell and cell-attached recordings from neurons in slices of rat somatosensory cortex, we demonstrate that transient ...
Gulledge, Allan T, Stuart, Gregory J
openaire   +3 more sources

Analysis of Mouse Brain Sections by Live-cell Time-lapse Confocal Microscopy

open access: yesBio-Protocol, 2023
The developing cerebral cortex of mammals is generated from nascent pyramidal neurons, which radially migrate from their birthplace in the ventral part of the neural tube to the cortical surface.
Tao Yang, Ty Hergenreder, Bing Ye
doaj   +1 more source

Stereology neuron counts correlate with deep learning estimates in the human hippocampal subregions

open access: yesScientific Reports, 2023
Hippocampal subregions differ in specialization and vulnerability to cell death. Neuron death and hippocampal atrophy have been a marker for the progression of Alzheimer’s disease.
Jan Oltmer   +8 more
doaj   +1 more source

Size of hippocampal pyramidal neurons in schizophrenia [PDF]

open access: yesBritish Journal of Psychiatry, 2003
BackgroundMeta-analyses of hippocampal size have indicated that this structure is smaller in schizophrenia. This could reflect a reduction in the size of constituent neurons or a reduced number of neurons.AimsTo measure the size of hippocampal pyramidal neurons in the brains of people with and without schizophrenia.MethodPyramidal neuron size in ...
Highley, JR   +4 more
openaire   +4 more sources

Neurons as Canonical Correlation Analyzers

open access: yesFrontiers in Computational Neuroscience, 2020
Normative models of neural computation offer simplified yet lucid mathematical descriptions of murky biological phenomena. Previously, online Principal Component Analysis (PCA) was used to model a network of single-compartment neurons accounting for ...
Cengiz Pehlevan   +4 more
doaj   +1 more source

Fractional differentiation by neocortical pyramidal neurons [PDF]

open access: yesNature Neuroscience, 2008
Neural systems adapt to changes in stimulus statistics. However, it is not known how stimuli with complex temporal dynamics drive the dynamics of adaptation and the resulting firing rate. For single neurons, it has often been assumed that adaptation has a single time scale.
Lundstrom, Brian Nils   +3 more
openaire   +2 more sources

The dendritic density field of a cortical pyramidal cell [PDF]

open access: yes, 2012
Much is known about the computation in individual neurons in the cortical column. Also, the selective connectivity between many cortical neuron types has been studied in great detail.
Hermann Cuntz   +3 more
core   +1 more source

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