Results 41 to 50 of about 44,043 (291)

The iso-Nazarov reaction [PDF]

open access: yes, 2017
The construction of five-membered rings is essential in organic chemistry. In this context, pentannulation reactions that provide a straightforward access to cyclopentenones are of particular interest, as these structures are not only embedded in ...
Marsili, Lucía A.   +2 more
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Efficient one-pot catalyst-free synthesis of novel coumarin- spiro[indoline-3,4'-pyran] conjugates via three-component domino reaction in aqueous medium

open access: yesGreen Chemistry Letters and Reviews, 2019
A simple, efficient, eco-friendly and catalyst-free procedure was developed for the construction of novel coumarin-spiro[indoline-3,4'-pyran] conjugates via three-component reactions of various synthetic beta-ketoesters with isatins and malononitrile in ...
Adil Omar, Keyume Ablajan
doaj   +1 more source

Effects of Pyran-Ring Structure in Carbon Sources on the Electrochemical Performance of LiFePO4/C

open access: yesInternational Journal of Electrochemical Science, 2013
Nano-sized LiFePO4/C (LFP/C) with excellent electrochemical performance was prepared by using carbon precursors with different pyran-ring structures as carbon sources.
Baohua Li   +9 more
doaj   +1 more source

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. [PDF]

open access: yes, 2019
ObjectiveMicroglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing ...
Bushong, Trevor   +8 more
core   +2 more sources

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci   +13 more
wiley   +1 more source

PRENYLATED XANTHONES FROM Rheedia acuminata (reprinted from Acta Amazônica, 23(2/3):181-185) [PDF]

open access: yesActa Amazonica, 1994
Pyranojacareubin; 1,5-dihydroxy-6',6'-dimethyl-2H-pyran(2,,3':6,7) -6",6"-dime-thyl-2H,4H-pyran(2",3":2,3)xanthone and a new xanthone l,6-dihydroxy-5-methoxy-6',6'-dime-thyl-2H-pyran(2',3':3,2)-7-(3,3-dimethylprop-2-enyl)xanthone were isolated from the ...
Maria das G. B. ZOGHBI   +3 more
doaj   +1 more source

Preparation, Structure, and Reactivity of Nonstabilized Organoiron Compounds. Implications for Iron-Catalyzed Cross Coupling Reactions [PDF]

open access: yes, 2008
A series of unprecedented organoiron complexes of the formal oxidation states −2, 0, +1, +2, and +3 is presented, which are largely devoid of stabilizing ligands and, in part, also electronically unsaturated (14-, 16-, 17- and 18-electron counts ...
Fürstner, A.   +5 more
core   +1 more source

Novel One-Pot Synthesis of Pyrazolopyranopyrimidinones Using Newly Produced γ-Alumina Nanoparticles as Powerful Catalyst [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2018
g-Alumina nanoparticles (g-Al2O3 NPs) were prepared via a new and simple synthetic route and characterized by field emission scanning electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy.
Sajad Kiani   +4 more
doaj  

Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]

open access: yes, 1984
We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core   +2 more sources

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