Molecules, 2015 In this work, 3-bromoacetylcoumarin was used as the key starting material for the synthesis of pyran, pyridine, thiophene, thiazole and pyrazole derivatives through its reaction with different reagents.
Rafat M. Mohareb, Nadia Y. MegallyAbdo
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Quantitative Structure-Property Relationships for Predicting the Retention Indices of Fragrances on Stationary Phases of Different Polarity [PDF]
, 2017 El objetivo de este trabajo fue el desarrollo de relaciones cuantitativas estructura–propiedad predictivas para el modelado de índices de retención (I) de fragancias, medidas en tres fases estacionarias de diferente polaridad: DB–225MS, HP5–MS y HP–1. Se
Duchowicz, Pablo Román +3 more
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Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
, 2013 Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill +48 more
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Allyl 6-amino-4-(4-chlorophenyl)-5-cyano-2-methyl-4H-pyran-3-carboxylate
IUCrData, 2019 In the title compound, C17H15ClN2O3, the 4H-pyran ring exhibits a shallow-boat conformation and the chlorobenzene ring occupies an axial position. The O-allyl side chain is disordered over two orientations in a 0.585 (14):0.415 (14) ratio. In the crystal,
G. Anantha Krishnan +4 more
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Acta Crystallographica Section E: Crystallographic Communications, 2019 In the title compounds, C32H25ClN2O4 (I) and C33H28N2O5 (II), the six-membered pyran and piperidine rings adopt envelope and chair conformations, respectively. The five-membered pyrrolidine rings adopt twist conformations. Compound (II) crystallizes with
S. Syed Abuthahir +4 more
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Heterogenisation of ketone catalysts within mesoporous supports for asymmetric epoxidation
, 2013 The synthesis of the first mesoporous silica (150 Å) anchored carbohydrate-derived chiral ketone is described. This new heterogeneous catalyst has been shown to be effective in the asymmetric epoxidation of olefins by oxone.
Adam +60 more
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Application of Transition Metal Catalysis to Small Molecule Synthesis [PDF]
, 2006 Over the past decade, transition metal catalysis has developed into a new field in organic synthesis, enabling numerous synthetic transformations that were previously not feasible.
Morrill, Christie
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Acta Crystallographica Section E: Crystallographic Communications, 2019 The title compound, C11H8O5·(CH3)2SO, is a new coumarin derivative. The asymmetric unit contains two coumarin molecules (A and B) and two dimethylsulfoxide solvent molecules (A and B).
S. Syed Abuthahir +4 more
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Synthesis of Enantiopure Oxygen- and Nitrogen-Containing Heterocycles by Diastereoselective Ring-Closing Metathesis Reaction in Perhydro-1,3-benzoxazine Derivatives [PDF]
, 2019 Producción CientíficaDiastereoselective ring‐closing metathesis reactions on chiral trienic perhydro‐1,3‐benzoxazines derived from (−)‐8‐aminomenthol featuring two diastereotopic olefin chains is described.
Andrés Juan, Celia +4 more
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Modeling Pyran Formation in the Molybdenum Cofactor: Protonation of Quinoxalyl–Dithiolene Promoting Pyran Cyclization [PDF]
Inorganic Chemistry, 2019 Mononuclear Mo and W enzymes require a unique ligand known as molybdopterin (MPT). This ligand binds the metal through a dithiolene chelate, and the dithiolene bridges a reduced pyranopterin group. Pyran scission and formation have been proposed as a reaction of the MPT ligand that may occur within the enzymes to adjust reactivity at the Mo atom.
Douglas R. Gisewhite +4 more
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