Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Jennifer Keiser +5 more
doaj +3 more sources
Effect of combinations of marketed human anthelmintic drugs against
Parasites & Vectors, 2012 Background Soil-transmitted helminth (STH) infections are responsible for a huge public health burden, however treatment options are limited. The discovery and development of novel efficacious drugs or drug combinations for the treatment of STH ...
Keiser Jennifer +3 more
doaj +2 more sources
Efficacy of pyrantel pamoate and ivermectin for the treatment of canine nematodes [PDF]
Semina: Ciências Agrárias, 2015 This study evaluated the efficacy of pyrantel pamoate and ivermectin on gastrointestinal nematodes in dogs. Fecal egg counts per gram (EPG) were measured by the fecal egg count reduction test (FECRT) in order to evaluate the anthelmintic efficiency and ...
Ana Paula Jesus +5 more
doaj +2 more sources
Simultaneous estimation of pyrantel pamoate, praziquantel & febantel by high performance liquid chromatography using dual wavelength [PDF]
Journal of Applied Pharmaceutical Research, 2014 A sensitive, fast, and stability-indicating gradient reverse-phase liquid chromatography method was developed for quantitative simultaneous estimation of Pyrantel pamoate, Praziquantel and Febantel using reverse phase high performance liquid ...
Rupali Sajjanwar +3 more
doaj +3 more sources
Treatment and control of Haemaphysalis longicornis infestations on dogs using a formulation of sarolaner, moxidectin and pyrantel (Simparica Trio®) [PDF]
Parasites & VectorsBackground Simparica Trio ® (Zoetis), an orally administered combination product for dogs containing sarolaner, moxidectin and pyrantel pamoate, was evaluated against Haemaphysalis longicornis, a tick species originally native to Asia but now found on ...
Kristina Kryda +4 more
doaj +2 more sources
Efficacy of a novel chewable tablet (Credelio Quattro™) containing lotilaner, moxidectin, praziquantel, and pyrantel for the treatment and control of hookworm infections in dogs [PDF]
Parasites & VectorsBackground Hookworms, specifically Ancylostoma caninum and Uncinaria stenocephala, have a clinical impact on the health of dogs, with A. caninum posing a zoonotic risk worldwide.
Samuel Charles +8 more
doaj +2 more sources
Efficiency of anthelmintic treatment and its effect on microparasite dynamics in wild Mastomys natalensis [PDF]
International Journal for Parasitology: Parasites and WildlifeCo-infections between helminths and microparasites can modulate the host immune response and alter disease dynamics, with potential implications for public health. However, identifying causal relationships in natural populations is challenging due to the
Marre van de Ven +5 more
doaj +2 more sources
Long-term safety of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets), a novel orally administered combination endectocide for dogs [PDF]
Parasites & VectorsBackground The combination of lotilaner, moxidectin, praziquantel, and pyrantel pamoate (Credelio Quattro) is a novel systemic endectocide that provides month-long effectiveness in dogs after a single oral treatment.
Kari L. Riggs +2 more
doaj +2 more sources
Modeling transmission mechanism to infer treatment efficacy of different drugs and combination therapy against Trichuris trichiura [PDF]
Scientific ReportsTrichuris trichiura is one of four soil-transmitted helminth species that, collectively, are responsible for a considerable public health burden. The World Health Organization recommends preventive chemotherapy as the main intervention to eliminate soil ...
Carla M. Grolimund +6 more
doaj +2 more sources
Endoscopic Diagnosis of <i>Necator americanus</i> Infection Presenting With Persistent Iron-Deficiency Anemia: Usefulness of Image-Enhanced Endoscopy and Capsule Endoscopy. [PDF]
DEN OpenABSTRACT Necator americanus infection is now rare in developed countries but remains an important cause of iron‐deficiency anemia and abdominal symptoms in individuals with relevant epidemiological backgrounds. A 59‐year‐old Filipino man with long‐standing unexplained iron‐deficiency anemia was admitted to our hospital for epigastric pain associated ...
Takebe T +9 more
europepmc +2 more sources