Results 171 to 180 of about 1,937,826 (232)

Synthesis, X-Ray Analysis, Anticancer Activity, Computational, and in Silico Studies of New Thiophene Pyrazole Conjugates. [PDF]

ChemistryOpen
Muhsinah AB, Kheder NA, Elhaty IA, Mabkhot YN.   +3 more
europepmc   +1 more source

Structure-activity relationship of pyrazole-based corrosion inhibitors for carbon steel in HCl: combined experimental and theoretical study. [PDF]

Sci Rep
Khedr BMA, Ramadan SK, Abdelkader SA, Abdelhamed S, El-Etre MA, Ibrahim MAM, Tammam RH, Nasser A.   +7 more
europepmc   +1 more source

Design and synthesis of 1,3,4-oxadiazole-tethered <i>N</i>-substituted isatin hybrids as SARS-CoV-2 main protease inhibitors: biological evaluation, kinetic investigation, and <i>in silico</i> studies. [PDF]

RSC Adv
Al-Warhi T, Islam Mukim MS, Elsayed ZM, Omar YM, Elimam DM, Shaldam MA, El-Damasy AK, Elbadawi MM, Tawfik HO, Song DG, Eldehna WM.   +10 more
europepmc   +1 more source

Exploring Novel Indazole and Pyrazole Nucleoside Analogues: Enzymatic Synthesis, Characterization, and Biological Evaluation. [PDF]

Int J Mol Sci
Mironov AF, Eletskaya BZ, Antonov KV, Paramonov AS, Esipov RS, Konstantinova ID, Andreevskaya SN, Smirnova TG, Karpenko IL, Sokhraneva VA, Zhivotova IS, Kochetkov SN, Khandazhinskaya AL, Matyugina ES.   +13 more
europepmc   +1 more source

The Pyrazole Scaffold in Anticancer Drug Discovery: A Review of Synthetic Approaches, Structure-Activity Relationships, and Target-Based Mechanism of Action. [PDF]

Int J Mol Sci
K R K, Hacholli VB, Gackowski M, Pisklak DM, Kumar A, Szeleszczuk Ł.   +5 more
europepmc   +1 more source

Unlocking the Potential of Isatin Scaffolds in Acetylcholinesterase Inhibition. [PDF]

Arch Pharm (Weinheim)
Tharwat T, El-Nassan HB, Adly ME, Kamel MM.   +3 more
europepmc   +1 more source

Improving the metabolic stability of a selective mTOR inhibitor through scaffold deconstruction and carbamate exploration. [PDF]

RSC Med Chem
Lorente-Macías Á, Mok J, Frame MC, Unciti-Broceta A.   +3 more
europepmc   +1 more source

Design, synthesis, molecular docking and molecular dynamics simulations of pyrazolo[3,4-<i>d</i>]pyrimidine scaffolds as selective COX-2 and CDK2 kinase inhibitors with dual anti-inflammatory and anti-proliferative activities. [PDF]

RSC Adv
Ewieda SY, Ziko L, Elshewy A, Salem M, Ibrahim ML, Lotfy Khaled M, Abdalla M, Eltayb WA, Elnagar MR, Tawfik MM, Abdullah Alzahrani AY, Nemr MTM.   +11 more
europepmc   +1 more source