Results 151 to 160 of about 1,937,826 (232)

Advances in N- and S-Heterocycles as c-Jun-N-Terminal Kinase 3 Inhibitors for Alzheimer's Disease Treatment. [PDF]

Drug Dev Res
Yadav P, Mishra D, Singh R.
europepmc   +1 more source

Novel Pyrazole-4-Carbaldehyde Derivatives Having Potent COX-2 Inhibition and Anti-Tubercular Activity: Microwave-Assisted Green Synthesis and Molecular Docking. [PDF]

J Biochem Mol Toxicol
Kokane M, Bhosale D, Raut D, Hadimani P, Narale A, Choudhari P, Lawand A.   +6 more
europepmc   +1 more source

Synthesis, characterization, docking and <i>in vitro</i> evaluation of new pyrazole-carboxylate derivatives as antibacterial, anticancer and anti-inflammatory agents. [PDF]

RSC Adv
Menezes RA, Ellyan NS, M M, Pai KN, Alex AT, Kulal A, Vasudeva PK, Bhat KS.   +7 more
europepmc   +1 more source

Synthesis and molecular docking of novel pyrazole, pyrimidine, and pyridine derivatives as potent antimicrobial, antibiofilm, and anticancer agents. [PDF]

Sci Rep
Hassan AMA, Essam ES, Hamed S, Helal MH, El-Ziaty AK, Ali RS.   +5 more
europepmc   +1 more source

Store-Operated Calcium Entry Inhibitors: Structural Diversity, Mechanisms of Action, and Optimization Strategies. [PDF]

Int J Mol Sci
Zakharova AA, Grekhnev DA, Kaznacheyeva EV, Vigont VA.   +3 more
europepmc   +1 more source

Proteolysis Targeting Chimera (PROTAC) Linkerology Enhances the CDK-Degradation Selectivity Profile of a Multi-CDK Inhibitor: Discovery of Potent, Anti-Leukemic CDK9 Degraders. [PDF]

ACS Pharmacol Transl Sci
Chan AM, Eberly C, Goodis CC, Nordquist EB, Weldemariam M, Carter-Cooper BA, Pogash S, Lapidus R, Kane MA, MacKerell AD, Civin CI, Fletcher S.   +11 more
europepmc   +1 more source

Recent advances in thiazole-based derivatives targeting diverse anti-inflammatory pathways. [PDF]

RSC Adv
Dawood DH, Al-Hussain SA, Farghaly TA, Alsaedi AMR, Zaki MEA.   +4 more
europepmc   +1 more source

Design, Synthesis, and Applications of Pyrazabole Functionalized Derivatives. [PDF]

Chem Asian J
Tiwari NJ, Rana KP, Misra R.
europepmc   +1 more source

Targeting CDK-2 With Novel Indole-Pyrazole Hybrids: Discovery of Potent Anticancer Agents Supported by Mechanistic and In Silico Studies. [PDF]

Drug Dev Res
Eldehna WM, Elsayed ZM, Elnagar MR, Omar YM, Abdulla MH, Saleh AM, Shalabi AR, Elimam DM, Alshamari S, Fares M, Tawfik HO.   +10 more
europepmc   +1 more source

Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure-activity relationships, molecular docking, and DFT studies. [PDF]

Sci Rep
Sallam MN, Hassan AMA, Alzahrani AYA, El-Masry HM, El-Naggar AM, Abbass EM.   +5 more
europepmc   +1 more source