Results 81 to 90 of about 27,892 (233)
Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites
ChemMedChem, EarlyView.Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert +6 more
wiley +1 more source
Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
ChemMedChem, Accepted Article.The efficient photochemical synthesis of bicyclic pyrazolines using flow technology as well as the subsequent antimicrobial evaluation of these scaffolds is reported. Low MIC values of 0.5‐4 μg/mL were found against a series of multidrug resistant bacterial strains including different Staphylococcus and Enterococcus genera species The lead compound ...
Debora Caviglia +4 more
wiley +1 more source
Pyrazole Studies. XI. Oxidation by Air of 1:4-Disubstituted Pyrazolidine-3:5-diones. [PDF]
, 1958 Stig Veibel +5 more
openalex +1 more source
Chemistry–Methods, EarlyView.An efficient mechanochemical route for diphenyleneiodonium (DPI) salt synthesis is reported which offers a sustainable and solvent‐free alternative. The solid‐state reactivities of the reported DPI salts were also assessed with the help of morphology predictions and Hirshfeld surface analysis computations to understand the effect of crystal morphology,
Ipsha Shruti, Tejender S. Thakur
wiley +1 more source
Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity
Molecules, 2019 To find novel antitumor agents, a series of 1H-benzofuro[3,2-c]pyrazole derivatives 4a-e were designed and synthesized. The treatment of 6-methoxybenzofuran-3(2H)-one 3 with LiHMDS in anhydrous tetrahydrofuran (THF) followed by reaction with 3-substitued
Ying-Jie Cui +3 more
doaj +1 more source
Studies on Pyrazolones. X. Reactions of Pyrazole Blue with Cyanoacetamide and Malononitrile. [PDF]
, 1956 Gunnel Westöö +4 more
openalex +1 more source
ChemPlusChem, EarlyView.One‐dimensional Pt(II) complexes are known to exhibit significant thermochromic emissions in the crystalline state. This phenomenon offers valuable insights into the excited states of Pt(II) complexes. This review focuses on the thermochromic mechanisms of one‐dimensional Pt(II) and Pd(II) complexes from the viewpoint of the relationship between ...
Masaki Yoshida, Masako Kato
wiley +1 more source
Die Übertragung der Friedel‐Craftsschen Keton‐Synthese auf Pyrazole [PDF]
, 1917 A. Michaelis, C. A. Rojahn
openalex +1 more source
ChemSusChem, Accepted Article.Developing a selective lignin depolymerization process remains a daunting challenge due to lignin's inherent structural heterogeneity and chemical complexity. This study employed a novel deep eutectic solvent (DES) extraction to produce oligomeric lignin with controlled structural characteristics (narrow size distribution, lower molecular weight) and ...
Udishnu Sanyal +6 more
wiley +1 more source