Results 161 to 170 of about 4,108 (208)

Discovery of Pyrazoline Benzenesulfonamide Derivatives as Anticancer Agents: A Review. [PDF]

Drug Des Devel Ther
Hasyim DM, Musfiroh I, Hendra R, Kamarulzaman EE, Ritmaleni R, Muchtaridi M.   +5 more
europepmc   +1 more source

Design, synthesis, antiproliferative activity, and molecular dynamics simulation of pyrazoline-based derivatives as dual EGFR and HER-2 inhibitors. [PDF]

RSC Adv
Hafez HM, Said BAM, Sayed AM, Alatwi E, Youssif BGM, Bräse S, El-Sherief HAM.   +6 more
europepmc   +1 more source

Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents. [PDF]

Sci Rep
Yadav CS, Krishna A, Singh SP, Kishan J, Chopra S, Srivastava K, Guha R, Lohani MB, Ahmad V, Alghamdi AA, Khan AR, Azad I.   +11 more
europepmc   +1 more source

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Four substituted pyrazolines

Acta Crystallographica Section C Crystal Structure Communications, 2007
In the title compounds 5-(3-fluoro-4-phenoxyphenyl)-1,3-biphenyl-4,5-dihydro-1H-pyrazole, C27H21FN2O, (I), 3-(4-chlorophenyl)-5-(3-fluoro-4-phenoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole, C27H20ClFN2O, (II), 5-(3-fluoro-4-phenoxyphenyl)-3-(4-methylphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole, C28H23FN2O, (III), and 5-(3-fluoro-4-phenoxyphenyl)-3-(4 ...
Chopra, Deepak, Mohan, TP, Vishalakshi, B, Row, Guru TN   +3 more
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Steroidal pyrazolines

Journal of Heterocyclic Chemistry, 1978
AbstractReaction of 21‐benzal‐5‐pregnen‐3β‐ol‐20‐one acetate with phenylhydrazine or p‐methoxy‐phenylhydrazine in the presence of hydrochloric acid yielded 3β‐aeetoxy‐1′,5′ ‐diphenyl‐5‐preg‐neno[20,21‐c]pyrazoline. Alkaline hydrolysis of the 3β‐acetoxy group followed by Oppenauer oxidation furnished the 3‐oxo‐1′,5′‐diphenyl‐4‐pregneno[20, 21‐c ...
Panayotis Catsoulacos, C. I. Stassinopoulou   +1 more
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Pyrazolines: A Biological Review

Mini-Reviews in Medicinal Chemistry, 2013
Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively researched upon. The ring is quite stable and has inspired chemists to carry out various structural variations in the ring. This has propelled the development of distinct pyrazolines with an array of pharmacological activities viz.
Akranth, Marella, Md Rahmat, Ali, Md Tauquir, Alam, Rikta, Saha, Omprakash, Tanwar, Mymoona, Akhter, Md, Shaquiquzzaman, M Mumtaz, Alam   +7 more
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TBD-organocatalysed synthesis of pyrazolines

Organic & Biomolecular Chemistry, 2009
It was found that TBD, a cheap and commercially available guanidine, easily catalysed the synthesis of biologically important 3,5-diarylpyrazolines from chalcones and acylhydrazines via a selective secondary amine alkylation.
Mahé, Olivier, Frath, Denis, Dez, Isabelle, Marsais, Francis, Levacher, Vincent, Brière, Jean-François   +5 more
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New Pyrazoline Derivatives

Collection of Czechoslovak Chemical Communications, 1994
The biological activity of azoles, pyrimidines as well as pyrazolines are of interest. Formation of pyrazolines and related compounds from hydrazine derivatives and α,β-unsaturated carbonyl compounds is very common. Pyrazoline fused with different heterocyclic nuclei at position 4 and 5 have been reported.
F. M. Abd El Latif, A. S. Maghraby, M. A. Barsy, M. Z. A. Badr, D. Dopp   +4 more
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PYRAZOLINES: PART II

Canadian Journal of Chemistry, 1960
Product analysis has been carried out on the pyrolysis reaction in the liquid and vapor phase of 4- and 5-methyl-3-carbomethoxy-Δ2-pyrazolines and 3-methyl-3-carbomethoxy-Δ1-pyrazoline. The proportion of cyclopropane product was found to be greater than earlier reports had indicated and was higher for the vapor-phase pyrolysis than for the liquid ...
Donald E. McGreer, Wing Wai, George Carmichael   +2 more
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4-Isopropylidene-3,3,5,5-tetramethyl-Δ1-pyrazoline - an almost flat pyrazoline

Tetrahedron Letters, 1982
Abstract The X-ray crystallographic structure of the title compound 6 shows that it is almost planar. This helps to explain a number of peculiar features in the chemistry of α-methylated pyrazolines.
Richard J. Bushby, Stephen Mann, Walter S. McDonald   +2 more
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