Results 91 to 100 of about 2,698 (209)

Pyridazine and its related compounds. Part 35 [1]: Synthesis, characterization and antimicrobial activity of some novel pyridazine and triazolopyridazine containing sulfonamides [PDF]

, 2015
The present study describes the chemical synthesis and antimicrobial evaluation of some new pyridazine and triazolopyridazine derivatives. The structure assignments of the new compounds are based on chemical and spectroscopic evidences. The Study results
El-Eraky, Wafaa Ibrahim, Mohamed, Sebaey Mahgoub, Deeb, Ali AbdelHamid   +2 more
core   +1 more source

Facile Synthesis and Antimicrobial Evaluation of Some New Heterocyclic Compounds Incorporating a Biologically Active Sulfamoyl Moiety

The Scientific World Journal, 2014
A facile and convenient synthesis of new heterocyclic compounds containing a sulfamoyl moiety suitable for use as antimicrobial agents was reported. The precursor 3-oxo-3-phenyl-N-(4-sulfamoylphenyl)propionamide was coupled smoothly with arenediazonium ...
Elham S. Darwish
doaj   +1 more source

Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping. [PDF]

J Med Chem, 2023
Břehová P, Řezníčková E, Škach K, Jorda R, Dejmek M, Vojáčková V, Šála M, Kovalová M, Dračínský M, Dolníková A, Strmeň T, Kinnertová M, Chalupský K, Dvořáková A, Gucký T, Mertlíková Kaiserová H, Klener P, Nencka R, Kryštof V.   +18 more
europepmc   +1 more source

Heterocyclic synthesis with ω-bromoacetophenone: Synthesis of some new pyrazole, pyridazine and furan derivatives

, 2008
p-Bromophenacylnitrile derivatives 3a,b react with hydrazinederivatives under different conditions to afford the diaminopyrazoles 4a,b, the pyridazine-6-imines 5a,b,and 5-aminopyrazoles 11a,b.
Metwally, Nadia H., Abdelrazek, Fathy M., Abdallah, Tayseer A.   +2 more
core  

Synthesis and characterization of novel thienylpyridazine derivatives [PDF]

, 2014
We report the synthesis and the photophysical characterization of novel thienyl-pyridazine derivatives, functionalized in position 3, with different donor groups (thiophene, pyrrole and N,N-dialkylphenylamine).
M. Raposo, Sara Fernandes, Fernades, Sara S. M., Fernandes, Sara Sofia Marques, Fernandes, S. S. M., Fernandes, Sara S. M., Raposo, M. Manuela M.   +6 more
core   +1 more source

Pyrrolo-pyridazine Derivatives as Muscarinic M₁ Receptor Positive Allosteric Modulators. [PDF]

ACS Med Chem Lett, 2021
Blass BE.
europepmc   +1 more source

Ring-chain transformation of 4-aroyl-5-phenylamino-2,3-dihydrothiophene-2,3-diones: Facile and efficient synthesis of novel pyrrolo[2,3-c]pyrazol-3(2H)-ones and 1,2-dihydro-5H,6H-pyridazine-5,6-diones

, 2019
Seven, novel pyrrolo[2,3-c]pyrazol-3(2H)-one and 1,2-dihydro-5H,6H-pyridazine-5,6-dione chromophores were synthesized by the reaction of 4-aroyl-5-phenylamino-2,3-dihydrothiophene-2,3-diones with cyanoacetohydrazide and arylhydrazines such as ...
Hassan Kabirifard (809064), Pardis Hafez Taghva (8127366)   +1 more
core   +1 more source

Synthesis, Anticancer Activities and Molecular Docking Studies of a Novel Class of 2-Phenyl-5,6,7,8-tetrahydroimidazo [1,2-b]pyridazine Derivatives Bearing Sulfonamides. [PDF]

Molecules, 2022
Bourzikat O, El Abbouchi A, Ghammaz H, El Brahmi N, El Fahime E, Paris A, Daniellou R, Suzenet F, Guillaumet G, El Kazzouli S.   +9 more
europepmc   +1 more source

Pyridazine derivatives and its related compounds. Part 31. Synthesis of some disperse dyes derived from 3-amino-1H-pyrzolo[3,4-c]pyridazine and their color assessment on polyester fabrics [PDF]

, 2014
The 6-methyl-3, 4-diphenyl-7-(2-phenylhydrazono) pyrimido [1', 2':1, 5] pyrazolo [3,4-c] pyridazin-8(7H)-one and 3,4-diphenyl-7-(phenyldiazenyl)pyrimido[1',2':1,5]pyrazolo[3,4-c]pyridazine-6,8-diamine derivatives were applied to polyester fiber as ...
Abdelgawad, Ahmed Awad Mohammed, El-Hossami, Mamdoh Bahgat, El‐Hossami, Mamdoh Bahgat, AbdelGawad, Ahmed Awad, Deeb, Ali AbdelHamid   +4 more
core   +1 more source

Synthesis and Anti Cancer Activity of Pyrido[2,3-c]Pyridazine Derivatives [PDF]

Journal of Sciences, Islamic Republic of Iran, 2009
Cancer is not just one disease, but a large group of almost one hundred diseases. Its two main characteristics are uncontrolled growth of the cells in the human body and the ability of these cells to migrate from the original site and spread to distant ...
V. Kumar
doaj