Results 81 to 90 of about 4,025 (222)

Synthesis and characterization of some heterocyclic including oxazoles,Thiazoles, Pyridazines, phthalizines and Pyrazoles with evaluating of biological activity.

مجلة بغداد للعلوم, 2013
A series of new compounds including p-bromo methyl pheno acetate [2]. N-( aminocarbonyl)–p-bromo pheno acetamide [3] , N-( aminothioyl) -p-bromo phenoacetyl amide [4], N-[4-(p-di phenyl)-1,3-oxazol-2-yl]-p-bromopheno acetamide [5],N-[4-p-di phenyl]-1,3 ...
Baghdad Science Journal
doaj   +1 more source

Synthesis of Pyridazines by Ring Transformation Reaction

, 2010
Charles University in Prague The Faculty of Pharmacy in Hradec Králové The Department of Inorganic and Organic Chemistry Candidate: Hana Budilová Supervisors: Doc. RNDr. Věra Klimešová, CSc. Prof. Dr.
Budilová, Hana
core  

Imidazo[1,2-b]pyridazines. XII. Syntheses and Central Nervous System Activities of Some Substituted Imidazo[1,2-b]pyridazines and Related Imidazo[1,2-a]pyridines, Imidazo[1,2-a]pyrimidines and Imidazo[1,2-a]pyrazines

, 1992
Syntheses are reported for some 6-chloro(alkoxy,alkylthio and pheny1thio)-3-benzamidomethyl-(acetamidomethyl and methoxy)-2-arylimidazo[1,2-apyridines and some corresponding imidazo- [1,2- b]pyridazines, imidazo[1,2-a[pyrimidines and imidazo[l,2-a ...
SJ Ireland, LP Davies, JK Zhang, GB Barlin, MML Ngu   +4 more
core   +1 more source

Imidazo[1,2-B]pyridazines. IX. Syntheses and Central Nervous System Activities of Some 3-Alkoxy-6-(o-alkoxy, o-methylthio- or o-fluoro-phenoxy)-2-arylimidazo[1,2-b]pyridazines

, 1990
Syntheses are reported for a series of 6-(o-methoxy -, o-ethoxy -, o-methylthio - and o-fluoro-phenoxy )-3-( methoxy and ethoxy )-2- phenyl(substituted phenyl and pyridin-3″-yl) imidazo [1,2-b] pyridazines .
SJ Ireland, CLY Khoo, LP Davies, GB Barlin, TMT Nguyen   +4 more
core   +1 more source

Switchable Ring-Contractive Extrusion Reactions of 2,5-Dihydro-1,4,5-thiadiazepine S‑Oxides: Entries to Pyridazines or Pyrazoles

, 2019
Switchable ring-contractive extrusion reactions of 2,5-dihydro-1,4,5-thiadiazepine S-oxides are described, which allow expedient access to pyridazines under thermal conditions or pyrazoles under Lewis acid-mediated ...
Bin Cheng (64483), Yuntong Li (4747326), Hongbin Zhai (1457509), Xinping Zhang (36283), Hui Li (32376), Taimin Wang (3856468), Yun Li (692280)   +6 more
core   +2 more sources

Development of novel antibiotics derived from pyridazine: Synthesis, spectroscopic characterization, in vitro antimicrobial activity and molecular docking studies

Results in Chemistry
In light of the increasing antibiotic resistance, it is crucial to discover new antimicrobial medications. Pyridazines are frequently investigated in research for the development of new chemical entities with enhanced therapeutic properties.
Mouad Lahyaoui, Mouad Filali, Khadija Benamar, Riham Sghyar, Kawtar Fikri-Benbrahim, Amal Haoudi, Ahmed Mazzah, Souad El khattabi, El Mestafa El Hadrami, Youssef Kandri Rodi, Nada Kheira Sebbar   +10 more
doaj   +1 more source

Pyridazines. XI. Pyrido[2, 3-d]pyridazines. II

Chemical and Pharmaceutical Bulletin, 1966
8-Oxo-7, 8-dihydropyrido[2, 3-d]pyridazine-5-carboxylic acid, 7-phenyl-8-oxo-7, 8-dihydropyrido[2, 3-d]pyridazine-5-carboxylic acid, and their esters, amides and hydrazides were prepared. Alkaline hydrolysis of 7-phenyl-8-oxo-7, 8-dihydroprido[2, 3-d]pyridazine-5-carboxylates gave phenylhydrazone of 3-formylpicolinic acid and good yields of 3-(2 ...
Matsuura, Ikutoshi, Yoneda, Fumio, Nitta, Yoshihiro   +2 more
openaire   +2 more sources

Imidazo[1,2-b]pyridazines. XIV. Syntheses and Central Nervous System Activities of Some 6-(Methoxy-, dimethoxy-, methylenedioxy-, chloro- and fluoro-)-3-alkoxy-2-phenyl(and substituted phenyl)imidazo[1,2-b]pyridazines

, 1993
Syntheses are reported for 28 new 3-alkoxy-6-(3′-methoxy-,3′,4′-dimethoxy, 3′,4′-methylene-dioxy-, 2′- and 4′-chloro- and 4′-fluoro-benzylamino)-2-phenyl(and substituted phenyl) imidazo -[1,2-b] pyridazines from the corresponding 6-substituted pyridazin-
SJ Ireland, LP Davies, JK Zhang, GB Barlin   +3 more
core   +1 more source

Synthesis and cytotoxic activity of some novel benzocoumarin derivatives under solvent free conditions

Green Chemistry Letters and Reviews, 2019
In the present study, a rapid, less expensive, clean and environmental friendly route to synthesis new pyrazoles, pyrazolopyridazines and condensed pyrimidines was developed via grinding of 2-(3-(dimethylamino)acryloyl)-3H-benzo[f]chromen-3-one (1) with ...
Anhar Abdel-Aziem, Huda Refaat Mahmoud Rashdan, Entesar Mohamed Ahmed, Sara N. Shabaan   +3 more
doaj   +1 more source

Copper-Catalyzed Aerobic 6‑Endo-Trig Cyclization of β,γ-Unsaturated Hydrazones for the Divergent Synthesis of Dihydropyridazines and Pyridazines

, 2019
A divergent synthetic strategy to 1,6-dihydropyridazines and pyridazines through Cu­(II)-catalyzed controllable aerobic 6-endo-trig cyclization was developed. The selectivity can be rationally tuned via the judicious choice of reaction solvent.
Zhangjin Pan, Zhenwei Fan, Jiajia Cheng (1623022), Liangsen Huang (5797064), Zhenwei Fan (6522803), Zhangjin Pan (6522806), Liangsen Huang, Jiajia Cheng   +7 more
core   +1 more source