Results 141 to 150 of about 148,723 (205)

Positional isomerization of pyridine through nitrogen transposition. [PDF]

Nature
Choi W, Ju H, Park J, Hong S.
europepmc   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source

Synthesis of 5-[3-amino-imidazo[1,2-<i>a</i>]pyridin-6-yl]pyridin-2-ones and derivatives through the combination of palladium-catalyzed cross-coupling and GBB multi-component reactions. [PDF]

RSC Adv
Caillet E, Chevrier Q, Retailleau P, Berteina-Raboin S, Gillaizeau I.   +4 more
europepmc   +1 more source

Click‐Spaltung quartärer Anilinium‐Tetrazine ermöglicht Kaskadenaufbau multifunktioneller biomolekularer Gerüste

Angewandte Chemie, EarlyView.
Die Click‐Chemie hat sich von dem Aufbau kovalenter Bindungen hin zum Spalten von Bindungen weiterentwickelt. Hier wird über einen Kaskaden‐Aufbau berichtet, der diese Verfahren kombiniert, um multifunktionale biomolekulare Gerüste in einer modularen Ein‐Topf‐Reaktion aufzubauen.
Markus Staudt, Christian B. M. Poulie, Andreas Löffler, Peter R. Meinig, Riley J. Deutsch‐Williams, Barbara Herrmann, Ralph Weissleder, Hannes Mikula, Jonathan C. T. Carlson, Matthias M. Herth   +9 more
wiley   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +1 more source

Design, synthesis, molecular docking and anticancer activity of novel <i>N</i>-(4-(chlorodifluoromethoxy)phenyl)-1<i>H</i>-pyrrolo[2,3-<i>b</i>]pyridine-5-carboxamide derivatives. [PDF]

RSC Adv
Bhise PB, Bhise SB, Dasgupta S, Nandy A, Gundla R, Gurska S, Dzubak P, Hajdúch M, Das V, Thopate SR, Badadhe PV.   +10 more
europepmc   +1 more source

Axial Boron Coordination Reconstructs Stereostructure of Cu Single‐Atom Nanozymes for Efficient Water‐Phase Chemical Sensing

Angewandte Chemie, EarlyView.
Sun et al. proposed an axial boron coordination strategy to reconstruct the stereostructure of Cu SAzymes and enable them to serve as efficient laccase mimics for high‐throughput smart sensor array detection of phenolic pollutants in water phases. ABSTRACT Developing single‐atom nanozymes with stereoconfigurations is a new paradigm for biomimetic ...
Qijun Sun, Hongyu Shi, Si Liu, Ziping Li, Yu Yang, Fengwang Li, Wenli Wu, Qiongzheng Hu, Kang Liang   +8 more
wiley   +1 more source

Z‐Retentive Enantioselective Rh‐Catalyzed Hydroarylation of E,Z‐Dienes

Angewandte Chemie, EarlyView.
The Rh‐catalyzed hydroarylation of conjugated E,Z‐dienoates is found to proceed with high selectivity for addition to the E‐alkene unit. Mechanistic analysis of this Z‐retentive process points towards preferred binding of the E‐alkene unit to a Rh‐aryl species to give rise to the observed selectivity and that Rh‐enolate protonolysis to be turnover ...
Wesley McNutt, Hima Kozhummal, Abdullah Al‐Mashqbeh, Alex Brown, Rylan J. Lundgren   +4 more
wiley   +1 more source

Machine learning-assisted molecular design for efficient ¹⁹F hyperpolarization. [PDF]

Chem Sci
Peng Q, Zheng L, Sun H, Xiong Y, Zheng Z, Cui X, Chen Z, Wang X.   +7 more
europepmc   +1 more source

Synthesis, In Vitro Cytotoxic Evaluation, DFT Calculation and Molecular Docking for Novel Pyridine Derivative Platinum Complexes. [PDF]

Chem Biodivers
Kutlu E, Kılıç D, Emen FM, Sezer CV, Kınaytürk NK, Kutlu HM.   +5 more
europepmc   +1 more source