Results 161 to 170 of about 148,723 (205)

Deciphering the Medicinal Chemistry Aspects of Akt Inhibitors for the Management of Cancer: Structure-Activity Relationship Frameworks, Landscapes, and Optimization Approaches. [PDF]

Chem Biodivers
Dhangar MS, Palkar MB.
europepmc   +1 more source

Aza‐Büchner–Curtius–Schlotterbeck Reaction Enables Selective Construction of Quaternary Carbon Centers

Angewandte Chemie International Edition, EarlyView.
We introduce the Aza‐Büchner–Curtius–Schlotterbeck (ABCS) reaction: A mild, catalyst‐free method for homologating aryl imines. Diverging from the traditional BCS mechanism, the diazo intermediate undergoes selective C─C insertion to form an all‐carbon quaternary center.
Simon O. Angerer, Vincent George, Aryaman Pattanik, Gaia Carpentiero, Tereza Morcinková, Julia Rehbein, Burkhard König   +6 more
wiley   +1 more source

Imidazo[1,2‑<i>a</i>]pyridines as Privileged Scaffolds: Synthetic Advances, Biological Activities, and Translational Challenges. [PDF]

ACS Omega
Antoniolli G, Chaguri R, Grabauskas LA, Arruda DC, Rodrigues T.   +4 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Molecular Interactions of Pyridine With Water: A Combined DFT Benchmarking and QTAIM Analysis. [PDF]

J Comput Chem
Baikété J, Tcheombe CG, Malloum A, Conradie J.   +3 more
europepmc   +1 more source

Synergistic Sorption of Gallium(III) and Scandium(III) Ions by the Interpolymer System of Poly(Acrylic Acid)/Poly(4-vinylpyr-idine) Hydrogels: Kinetics, Selectivity, and Mechanism. [PDF]

Molecules
Totkhuskyzy B, Jumadilov T, Khimersen K, Akhmetova A, Haponiuk J, Grazulevicius J.   +5 more
europepmc   +1 more source

Synthesis of Composite Molecules of a Co₄O₄ Cubane Complex and Perylenediimide Moieties. [PDF]

Chem Asian J
Nagata T, Ishikawa W.
europepmc   +1 more source

Synthesis and evaluation of 3,5-disubstituted isothiazolo[4,5-b]pyridines, pyrazolo[4,3-b]pyridines and isothiazolo[3,4-b]pyrazines as inhibitors of PIKfyve. [PDF]

Bioorg Chem
Gao LJ, Froeyen M, Lo CW, Tran DHN, Van Loy T, Schols D, Rozenski J, Dehaen W, Einav S, De Jonghe S.   +9 more
europepmc   +1 more source