In‐situ‐Konstruktion von Imidazopyridinium‐Fluoreszenzlabels für Biokonjugationen
Durch Chromophor‐Engineering von Isochinolinaldehyden entstehen TICT‐basierte fluorogene Farbstoffe für die In Situ Markierung unterschiedlicher (Bio‐)Moleküle mit großen Stokes‐Verschiebungen, die mit der Zellbildgebung kompatibel sind. ZUSAMMENFASSUNG Einfache, effiziente Transformationen fluorogenen Charakters, die unter biokompatiblen Bedingungen ...
Dongchen Du +7 more
wiley +1 more source
Differentiating Resistance from Formulation Failure: Isoniazid Instability and Poor Dissolution in Crushed Multi-Drug Paediatric Preparations. [PDF]
Samsodien H +3 more
europepmc +1 more source
Gold recycling from electronic waste using porous materials is an emerging concept to reduce the environmental impact of gold mining. In this work, we report the synthesis of a highly porous phenazine‐derived tetraoxa[8]circulene polymer and its utilization in gold capture and heterogeneous catalysis.
Patrick W. Fritz +4 more
wiley +1 more source
Decoding Carbon Dot Purity by Nuclear Magnetic Resonance
NMR spectroscopy tracks the removal of molecular and oligomeric impurities in carbon dots, enabling a (semi)quantitative evaluation of their purity through integrated peak analysis. ABSTRACT Carbon dots (CDs) have attracted increasing attention in recent years and have been widely explored in many fields.
Yalei Hu, Alberto Bianco
wiley +1 more source
Design, synthesis and antiproliferative, apoptotic, and immunomodulatory properties of new heteroaryl pyridine-linked 1,2,4-oxadiazoles as prospective dual EGFR/BRAF<sup>V600E</sup> inhibitors. [PDF]
Gomaa HAM +9 more
europepmc +1 more source
Intermolecular Electrophilic Germylation Using GeCl4 and Al2Cl6
While electrophilic aromatic substitution is well‐established for carbon and silicon‐based electrophiles, it is extremely underdeveloped for germanium. Herein we report the first effective intermolecular Germa–Friedel–Crafts reaction. The process can be modified to enable selective synthesis of the mono‐ or the di‐aryl germane derivatives, ArGeCl3 and ...
Justyna Łosiewicz +4 more
wiley +1 more source
Stepwise functionalization-induced molecular tweak unveiling multi-level thermochromic data encryption and fingerprint monitoring system. [PDF]
Barman D, Parui R, Iyer PK.
europepmc +1 more source
This work details the rapid generation (t ≤ 5 min) of size‐tunable, ultralow dispersity (Ð ≤ 1.01) 2D hexagonal nanosheets by self‐limiting polymerization‐induced crystallization‐driven self‐assembly (SL‐PI‐CDSA) of modular and templating poly(aryl isocyanide) block copolymers, with functions that permit post‐polymerization modifications. Specifically,
Randall A. Scanga +13 more
wiley +1 more source
Discovery of potent bisindole-based pyrazolopyridine derivatives as topoisomerase inhibitors: DNA damage induction and synergistic antileukemic activity. [PDF]
Eldehna WM +11 more
europepmc +1 more source
Thermally Controlled Chiral Supramolecular Polymorphism in Water
Using an amphiphilic oligo(phenyleneethynylene) derivative, we establish LCST‐coupled chirality as a strategy to regulate thermoresponsive supramolecular polymorphism in water. At room temperature, AggI forms discrete assemblies that transform into elongated helical fibers (AggII) near the LCST and subsequently to sheet‐like structures (AggIII) at ...
Zulema Fernández +6 more
wiley +1 more source

