Results 191 to 200 of about 197,331 (314)

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
Nonheme Fe enzyme isopenicillin N synthase was reprogrammed and evolved as an efficient nitrogen migratase IPNSNim, converting diverse azanyl esters to valuable l‐arylglycines with up to 16 000 TTN and 97:3 e.r. IPNSNim and ACCONim allowed enantiodivergent preparation of both l‐ and d‐arylglycines.
Ken Lin, Liu‐Peng Zhao, Shengchun Wang, Huichong Liu, Yu Zhang, Binh Khanh Mai, Peng Liu, Yang Yang   +7 more
wiley   +2 more sources

Cross-Electrophile Coupling of <i>N</i>-Hydroxyphthalimide Esters with Aryl Bromides Using an Inner-Sphere Homogeneous Reductant. [PDF]

J Am Chem Soc
Ganguli K, Cruz AR, Diccianni JB, García-Reynaga P, Weix DJ.   +4 more
europepmc   +1 more source

Pheophytinisation of eight chlorophyll derivatives in aqueous acetone [PDF]

, 1992
Mazaki, Hitoshi, Scheer, Hugo, Struck, Andreas, Takahashi, Terumi, Watanabe, Tadashi   +4 more
core   +1 more source

Making Blank Faces Expressive: Chemical Approaches to the Modification of Chemically Inert Peptides

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
As an alternative to the conventional approach, which combines amino acid monomers in a one‐by‐one fashion to peptide derivatives, the chemical modification of existing peptides has attracted significant attention in recent years. However, such approaches generally target the reactive functional groups in cysteine and lysine residues, particularly in ...
Yoshitaka Moriyama, Hikari Sada, Takeshi Nanjo   +2 more
wiley   +1 more source

Semi-Targeted Nuclear Magnetic Resonance Metabolomics via Parahydrogen-Induced Hyperpolarization for Enhanced Sensitivity to Metabolic Composition. [PDF]

J Am Chem Soc
Posthumus TB, Engelke UFH, Aspers RLEG, Merx J, Boltje TJ, Martens J, Wevers RA, Feiters MC, Rutjes FPJT, Tessari M.   +9 more
europepmc   +1 more source

Turn‐Induction in Peptides Incorporating Novel Cyrene‐Derived α,α‐Disubstituted Amino Acid

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Novel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Kajumee Bora Bhowal, Raphael Hitti, William D. Lubell   +2 more
wiley   +1 more source

In situ generated hydrogen-bonding microenvironment in functionalized MOF nanosheets for enhanced CO₂ electroreduction. [PDF]

Proc Natl Acad Sci U S A
Yang G, Huang J, Gu W, Lin Z, Wang Q, Kang R, Liu JY, Sun Z, Zheng X, Jiao L, Jiang HL.   +10 more
europepmc   +1 more source

Hydroxylamine-O-sulfonic acid - a versatile synthetic reagent [PDF]

, 1980
Wallace, RG
core  

A General Approach for Strained Ring Functionalization via Nucleophilic Catalysis. [PDF]

JACS Au
Wang P, Deng C, Luo Z, Chen D, Li AY, Li Y, Huang L, Yu P.   +7 more
europepmc   +1 more source

Expediting hit-to-lead progression in drug discovery through reaction prediction and multi-dimensional optimization. [PDF]

Nat Commun
Nippa DF, Atz K, Stenzhorn Y, Müller AT, Tosstorff A, Benz J, Binch H, Bürkler M, Haider A, Heer D, Hochstrasser R, Kramer C, Reutlinger M, Schneider P, Shema T, Topp A, Walter A, Wittwer MB, Wolfard J, Kuhn B, van der Stelt M, Martin RE, Grether U, Schneider G.   +23 more
europepmc   +1 more source