Selective Halogenation of Pyridines Using Designed Phosphine Reagents.
Journal of the American Chemical Society, 2020 Halopyridines are key building blocks for synthesizing pharmaceuticals, agrochemicals, and ligands for metal complexes, but strategies to selectively halogenate pyridine C-H precursors are lacking.
J. N. Levy +4 more
semanticscholar +1 more source
Synthesis of stereodefined 1-aryl(heteroaryl) substituted 1,2-bis(2-bromopyridin-3-yl)ethenes by selective tandem Suzuki-Miyaura Cross-coupling reactions [PDF]
, 2008 In this communication we show the preparation of stereodefined trisubstituted alkenes 2 can be achieved by sequential selective Suzuki-Miyaura reactions of 2-bromo-3-(2,2-dibromovinyl)pyridines.
Baldino, Salvatore +1 more
core +1 more source
Molecules, 2022 Pyridine, 1,3,4-thiadiazole, and 1,3-thiazole derivatives have various biological activities, such as antimicrobial, analgesic, anticonvulsant, and antitubercular, as well as other anticipated biological properties, including anticancer activity.
Amr S. Abouzied +7 more
doaj +1 more source
O,N,N-Pincer ligand effects on oxidatively induced carbon–chlorine coupling reactions at palladium [PDF]
, 2015 The syntheses of two families of sterically tuneable O,N,N pro-ligands are reported, namely the 2-(phenyl-2′-ol)-6-imine-pyridines, 2-(C6H4-2′-OH),6-(CMe[double bond, length as m-dash]NAr)C5H3N [Ar = 4-i-PrC6H4 (HL1a), 2,6-i-Pr2C6H3 (HL1b)] and the 2 ...
Cross, WB +4 more
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Molecules, 2021 Publications covering a new easy metal-free functionalization of pyridinoids (pyridines, quinolines, isoquinolines, acridine) under the action of the system of electron-deficient acetylenes (acetylenecarboxylic acid esters, acylacetylenes)/P-nucleophiles
Boris A. Trofimov +2 more
doaj +1 more source
Experimental and Theoretical Evidence for Nitrogen-Fluorine Halogen Bonding in Silver-Initiated Radical Fluorinations [PDF]
, 2019 We report experimental and computational evidence for nitrogen–fluorine halogen bonding in Ag(I)-initiated radical C–H fluorinations. Simple pyridines form [N–F–N]+ halogen bonds with Selectfluor to facilitate single-electron reduction by catalytic Ag ...
Baker, Sarah I +4 more
core +5 more sources
An Efficient Synthesis of Novel Pyrazole-Based Heterocycles as Potential Antitumor Agents
Applied Sciences, 2017 A new series of pyrazolylpyridines was prepared by reaction of ethyl-3-acetyl-1,5-diphenyl-1H-pyrazole-4-carboxylate with the appropriate aldehyde, malononitrile, or ethyl acetoacetate and an excess of ammonium acetate under reflux in acetic acid ...
Magda A. Abdallah +5 more
doaj +1 more source
[2,2′-Bipyridin]-6(1H)-one, a Truly Cooperating Ligand in the Palladium-Mediated C–H Activation Step: Experimental Evidence in the Direct C-3 Arylation of Pyridine [PDF]
, 2018 Producción CientíficaThe ligand [2,2′-bipyridin]-6(1H)-one (bipy-6-OH) has a strong accelerating effect on the Pd- catalyzed direct arylation of pyridine or arenes.
Albéniz Jiménez, Ana Carmen +2 more
core +4 more sources
Bohlmann-Rahtz Cyclodehydration of Aminodienones to Pyridines Using N-Iodosuccinimide
Molecules, 2010 Cyclodehydration of Bohlmann-Rahtz aminodienone intermediates using N-iodosuccinimide as a Lewis acid proceeds at low temperature under very mild conditions to give the corresponding 2,3,6-trisubstituted pyridines in high yield and with total ...
Mark C. Bagley, Christian Glover
doaj +1 more source
Quaterpyridine Ligands for Panchromatic Ru(II) Dye Sensitizers [PDF]
, 2012 A new general synthetic access to carboxylated quaterpyridines (qpy), of interest as ligands for panchromatic dyesensitized solar cell organometallic sensitizers, is presented.
Abbotto, Alessandro +6 more
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