Investigating operational stability and causes of cofactor release in fold type I amine transaminase. [PDF]
Protein SciAbstract Amine transaminases (ATAs) are pyridoxal phosphate (PLP) dependent biocatalysts frequently employed in chiral amine synthesis. Yields of ATA‐catalyzed reactions often suffer from low enzyme operational stability due to weak interactions between the ATA and the aminated cofactor pyridoxamine phosphate (PMP), which can leak from the active site ...
Feng X, Chau W, Master ER.
europepmc +2 more sources
Computer-Assisted Design of Environmentally Friendly and Light-Stable Fluorescent Dyes for Textile Applications. [PDF]
, 2019 Five potentially environmentally friendly and light-stable hemicyanine dyes were designed based on integrated consideration of photo, environmental, and computational chemistry as well as textile applications.
Chen, Guoqiang +2 more
core +1 more source
Quaternary Pyridinium Salts: A Review
Journal of Oleo Science, 2008 Cationic surfactants are being used in various applications industrially and domestically for a long time. Pyridinium salts come under the category of cationic surfactants. These are unsaturated heterocyclic compounds having different functional groups present either on pyridine ring or at nitrogen atom.
Parag, Madaan, Vinod K, Tyagi
openaire +3 more sources
Synthesis compounds of Thiopyran Pyridinium Perchlorate and studing its Bioactivity: Part1. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A synthesis Four Pyridinium perchlorate Compounds from reaction one mole pyrylium salt (product already) with one mole 2-Aminoethylenethiol in room temp.
Marwan Mohammed Farhan
doaj +1 more source
4-{(1E,3E)-4-[4-(Dimethylamino)phenyl]buta-1,3-dien-1-yl}-1-methylpyridin-1-ium iodide
IUCrData, 2016 The title molecular salt, C18H21N2+·I−, consists of a pyridinium cation and an I− anion. The cation exists in an E,E conformation with respect to the two C=C double bonds, and is roughly planar with the pyridinium ring being inclined to the benzene ring ...
S. John Sundaram +4 more
doaj +1 more source
The synthesis and characterization of polypeptide-adriamycin conjugates and its complexes with adriamycin. Part I [PDF]
, 1985 Poly(α-l-glutamic acid) (PGA) was grafted with amino acid and oligopeptide spacers up to 5 amino acids with the use of N,N'-carbonyldiimidazole and 2,3-dihydro-1,2-benz-isothiazole-3-on-1, 1-dioxide (saccharin) as an additive, and these polypeptides were
Eenink, M.J.D. +5 more
core +2 more sources
Gold amides as anticancer drugs: synthesis and activity studies [PDF]
, 2013 Modular gold amide chemotherapeutics: Access to modern chemotherapeutics with robust and flexible synthetic routes that are amenable to extensive customisation is a key requirement in drug synthesis and discovery.
Amagai +34 more
core +1 more source
<sup>18</sup>F-Radiopharmaceutical Diversification Enabled by Deaminative Cross-Electrophile Couplings. [PDF]
Angew Chem Int Ed EnglA general Ni‐mediated (C)sp2–(C)sp3 cross‐coupling expedites access to 18F‐radiopharmaceuticals, essential for positron emission tomography imaging and drug discovery. This late‐stage diversification approach was implemented across three user‐friendly automated protocols affording 18F‐radiotracers in sufficient quantities for imaging.
Ogilvy IF +13 more
europepmc +2 more sources
Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]
, 2014 Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K. +4 more
core +2 more sources
2-[5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-yl]pyridin-1-ium perchlorate
IUCrData, 2017 The cation of the title molecular salt, C12H9N4S+·ClO4−, is approximately planar, with the pyridine and pyridinium rings being inclined to the central thiadiazole ring by 6.51 (9) and 9.13 (9)°, respectively.
Abdelhakim Laachir +4 more
doaj +1 more source