Results 141 to 150 of about 7,788 (207)

Apixaban Use Before Kidney Transplantation: Is Reversal Necessary? [PDF]

Pharmacotherapy
Cotiguala L, Przybylski A, Linberger L, Brokhof M, Kenyon N, Joyce C, Dierker M, Ferguson K, Rech MA, Trotter C, Aguirre O, Lopez-Soler RI.   +11 more
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Clinical validation of a patient-friendly saliva microsampling approach to monitor perampanel levels in people with epilepsy. [PDF]

Epilepsia
Franco V, Dattrino F, Palmisani M, Tacchella F, Tartara E, De Giorgis V, Quaranta CA, Pasca L, Rota P, Russo E, Romigi A, Johannessen Landmark C, Fedele G, Tassorelli C, Nicotera P.   +14 more
europepmc   +1 more source

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Pyridones as Potential Antitumor Agents II: 4-Pyridones and Bioisosteres of 3-Acetoxy-2-pyridone

Journal of Pharmaceutical Sciences, 1980
Pyridone structural requirements for activity against murine P-388 leukemia have been extended to isosteric analogs of 3-hydroxy-4-pyridone, a compound previously found to have activity. An amino group can be substituted for the 3-hydroxyl function with retention of activity.
D R, Hwang, G R, Proctor, J S, Driscoll
openaire   +2 more sources

Lithiation of pyridones

Journal of the Chemical Society, Chemical Communications, 1985
Lithiation of 1-methyl-4-pyridone with n-butyl-lithium at -78 °C proceeds smoothly at the C-2 position and 2-substituted-4-pyridones (1c–j) are obtained by subsequent reaction with electorphiles; lithiation of 1-methyl-2-pyridone takes place predominantly at the N-methyl, the lithio-derivative reacting rapidly, even at -78 °C with starting pyridone to ...
Premji Patel, John A. Joule
openaire   +1 more source

ChemInform Abstract: PHOTOISOMERIZATION OF 4‐PYRIDONES TO 2‐PYRIDONES

Chemischer Informationsdienst, 1974
AbstractBestrahlung (Hg‐Mitteldrucklampe) der 4‐Pyridone (I) liefert die isomeren 2‐Pyridone (II) als Hauptprodukte, während die 4‐Pyridone (III) unter gleichen Bedingungen unverändert bleiben.
NOBUYUKI ISHIBE, JUN MASUI
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Tetrachlorobis(2-pyridone)-bis(μ2-2-pyridone)-dicopper

Acta Crystallographica Section C Crystal Structure Communications, 1993
In this structure two Cu II centres 3.4448 (11) A apart are bridged asymmetrically by two 2-pyridone ligands and each is further coordinated by three terminal ligands (two chlorides and one 2-pyridone). Each molecule has an approximate, non-crystallographic centre of symmetry.
A. J. Blake, R. E. P. Winpenny
openaire   +1 more source

Ambident Reactivities of Pyridone Anions

Journal of the American Chemical Society, 2010
The kinetics of the reactions of the ambident 2- and 4-pyridone anions with benzhydrylium ions (diarylcarbenium ions) and structurally related Michael acceptors have been studied in DMSO, CH(3)CN, and water. No significant changes of the rate constants were found when the counterion was varied (Li(+), K(+), NBu(4)(+)) or the solvent was changed from ...
Martin, Breugst, Herbert, Mayr
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Photoisomerization of 4-pyridones to 2-pyridones

Journal of the American Chemical Society, 1974
Nobuyuki Ishibe, Jun Masui
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DERIVATIVES OF 2-PYRIDONE

The Journal of Organic Chemistry, 1946
W, WENNER, J T, PLATI
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