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Pyridoxal and Salicylaldehyde Derivatives: Synthesis, Characterization, and Antifungal Potential Against Opportunistic Yeast Pathogens [PDF]

open access: yesMolecules
This study reports the synthesis, characterization, and antifungal evaluation of a series of pyridoxal and salicylaldehyde derivatives, using synthetic methodologies such as radical cyclizations and click chemistry. Compounds 6a and 6b, featuring a fused
Jairo Camacho   +7 more
doaj   +2 more sources

Phosphorescence of Pyridoxal

open access: hybridJournal of Biological Chemistry, 1969
Abstract The effect of pH on the relative distribution of pyridoxal structures in aqueous solution was examined by fluorescence spectroscopy. The hemiacetal structure, which is the predominant species at neutral pH, exhibits a symmetrical emission band at 378 mµ and is characterized by a quantum yield of 0.08.
John E. Wampler, Jorge E. Churchich
openalex   +3 more sources

Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate

open access: yesInternational Journal of Nanomedicine, 2012
A Filipowicz, S WołowiecDepartment of Cosmetology, University of Information Technology and Management in Rzeszów, Rzeszów, PolandBackground: Bioconjugates of a polyamidoamine (PAMAM) G3 dendrimer and an aldehyde were synthesized as
Filipowicz A, Wołowiec S
doaj   +6 more sources

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation [PDF]

open access: yesNature Communications
Many essential proteins require pyridoxal 5’-phosphate, the active form of vitamin B6, as a cofactor for their activity. These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and ...
Izabella A. Pena   +16 more
doaj   +2 more sources

Oxovanadium(IV) complexes of the pyridoxal Schiff bases: Synthesis, experimental and theoretical characterizations, QTAIM analysis and antioxidant activity [PDF]

open access: yesJournal of the Serbian Chemical Society, 2020
Two vanadyl complexes of the pyridoxal Schiff bases have been newly synthesized and characterized by several experimental methods, where the 4,4′-[1,4-butanediylbis-[(E)-nitrilomethylidyne])bis[5-hydroxy-6-methyl- -3-pyridinemethanol] and trans-4,4′-[1,2-
Ghorbani Parisa   +3 more
doaj   +1 more source

A Novel Two-Dimensional Liquid Chromatography Combined with Ultraviolet Detection Method for Quantitative Determination of Pyridoxal 5′-Phosphate, 4-Pyridoxine Acid and Pyridoxal in Animal Plasma

open access: yesAnimals, 2023
Vitamin B6 is an indispensable micronutrient in organisms and is widely distributed in blood, tissues, and organs. Changes in the content and ratio of vitamin B6 can affect the entire physiological condition of the body, so it becomes particularly ...
Rong-Ju Yang   +7 more
doaj   +1 more source

Metal complexes with Schiff-base ligands - pyridoxal and semicarbazide-based derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
The most important results of extensive studies (syntheses, spectral, magnetic, voltammetric and structural characteristics and biological activity) of metal complexes with pyridoxal semi-, thiosemi- and isothiosemicarbazones are reviewed.
VUKADIN M. LEOVAC   +3 more
doaj   +3 more sources

Formation of a macrocycle from dichlorodimethylsilane and a pyridoxalimine Schiff base ligand

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2021
The reaction of dichlorodimethylsilane with a polydentate Schiff base ligand derived from pyridoxal and 2-ethanolamine yielded the macrocyclic silicon compound (8E,22E)-4,4,12,18,18,26-hexamethyl-3,5,17,19-tetraoxa-8,13,22,27-tetraaza-4,18-disilatricyclo[
Uwe Böhme   +2 more
doaj   +1 more source

Lipopolyplex-Mediated Co-Delivery of Doxorubicin and FAK siRNA to Enhance Therapeutic Efficiency of Treating Colorectal Cancer

open access: yesPharmaceutics, 2023
Tumor metastasis is a major concern in cancer therapy. In this context, focal adhesion kinase (FAK) gene overexpression, which mediates cancer cell migration and invasion, has been reported in several human tumors and is considered a potential ...
Tilahun Ayane Debele   +3 more
doaj   +1 more source

(E)-4-(((2-amino-5-chlorophenyl)imino)methyl)-5-(hydroxy-methyl)-2-methylpyridin-3-ol and its Cu(II) complex: Synthesis, DFT calculations and AIM analysis [PDF]

open access: yesJournal of the Serbian Chemical Society, 2020
Herein, (E)-4-{[(2-amino-5-chlorophenyl)imino]methyl}-5-(hydroxymethyl)- 2-methylpyridin-3-ol [HL] Schiff base and its [Cu(L)Cl] complex were newly synthesized and characterized by several spectroscopic methods.
Yavari Morteza   +3 more
doaj   +1 more source

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