Results 11 to 20 of about 43,493 (297)

Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate

International Journal of Nanomedicine, 2012
A Filipowicz, S WołowiecDepartment of Cosmetology, University of Information Technology and Management in Rzeszów, Rzeszów, PolandBackground: Bioconjugates of a polyamidoamine (PAMAM) G3 dendrimer and an aldehyde were synthesized as
Filipowicz A, Wołowiec S
doaj   +6 more sources

Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase. [PDF]

PLoS ONE, 2012
Pyridoxal 5'-phosphate (PLP) is a cofactor for dozens of B(6) requiring enzymes. PLP reacts with apo-B(6) enzymes by forming an aldimine linkage with the ε-amino group of an active site lysine residue, thus yielding the catalytically active holo-B(6 ...
Mohini S Ghatge, Roberto Contestabile, Martino L di Salvo, Jigar V Desai, Amit K Gandhi, Christina M Camara, Rita Florio, Isabel N González, Alessia Parroni, Verne Schirch, Martin K Safo   +10 more
doaj   +3 more sources

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

Nature Communications
Many essential proteins require pyridoxal 5’-phosphate, the active form of vitamin B6, as a cofactor for their activity. These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and ...
Izabella A. Pena, Jeffrey S. Shi, Sarah M. Chang, Jason Yang, Samuel Block, Charles H. Adelmann, Heather R. Keys, Preston Ge, Shveta Bathla, Isabella H. Witham, Grzegorz Sienski, Angus C. Nairn, David M. Sabatini, Caroline A. Lewis, Nora Kory, Matthew G. Vander Heiden, Myriam Heiman   +16 more
doaj   +2 more sources

Experimental and theoretical evaluation of N-pyridoxal-salicylic acid hydrazide derived copper(II) complex with 2-methylimidazole

, 2022
This article deals with the experimental and theoretical evaluations of N-pyridoxal-salicylic acid hydrazide (H2pd-sah) 1 and its mixed-ligand copper(II) complex with 2-methylimidazole, [Cu(pd-sah)(MeImdH)] 2.
Aniteshma Chanpuria (12867738), Pushpendra Singh Jaget (12867732), Mahendra Kumar Parte (12867735), Abhilasha Shukla (12867741), Pradeep Kumar Vishwakarma (6319565), Ahad Ali (12867744), Deepak Kumar Rajak (4410526), Ram Charitra Maurya (4410523)   +7 more
core   +1 more source

Phosphorescence of Pyridoxal

Journal of Biological Chemistry, 1969
Abstract The effect of pH on the relative distribution of pyridoxal structures in aqueous solution was examined by fluorescence spectroscopy. The hemiacetal structure, which is the predominant species at neutral pH, exhibits a symmetrical emission band at 378 mµ and is characterized by a quantum yield of 0.08.
J E, Wampler, J E, Churchich
openaire   +2 more sources

Biosynthesis of food constituents: Vitamins. 2. Water-soluble vitamins: Part 1 - a review

Czech Journal of Food Sciences, 2007
This review article gives a survey of the generally accepted biosynthetic pathways that lead to water-soluble vitamins in microorganisms, plants and some animals.
Jan Velíšek, Karel Cejpek
doaj   +1 more source

Transamination of α-keto acids catalyzed by pyridoxals

上海师范大学学报. 自然科学版, 2016
In this paper,we designed and synthesized a series of pyridoxals tagged with different functional groups.The pyridoxals exhibited high catalytic activity in transamination of α-keto acids to obtain various amino acids in good yields.This transamination ...
CHEN Jing, ZHAO Junyu, ZHAO Baoguo
doaj   +1 more source

A Vibrational Analysis of Pyridoxal 5'-Phosphate Derivatives: Pyridoxal 5'-Phosphate-isopropylamine and Pyridoxal 5'-Phosphate-(<i>S</i>)-1-phenylethylamine. [PDF]

J Phys Chem B
The external aldimine, a pivotal Schiff base intermediate in pyridoxal 5′-phosphate (PLP)-dependent enzyme-catalyzed reactions, plays a central mechanistic role in the ω-transamination pathway used for the synthesis of chiral amines in pharmaceutical ...
Dosanjh RS, Parker SF, Collier P, Pushpanath A, York APE, Grainger D, Tailor SB, Johnson T, Hyde T, Waddell LJN, Sutherland A, Lennon D.   +11 more
europepmc   +2 more sources

Prebiotic Synthesis of Aspartate Using Life’s Metabolism as a Guide

Life, 2023
A protometabolic approach to the origins of life assumes that the conserved biochemistry of metabolism has direct continuity with prebiotic chemistry. One of the most important amino acids in modern biology is aspartic acid, serving as a nodal metabolite
Stuart A. Harrison, William L. Webb, Hanadi Rammu, Nick Lane   +3 more
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DFT, ADMET, molecular docking and molecular dynamics studies of pyridoxal [PDF]

, 2023
We report in silico studies of pyridoxal, which is of interest both as a precursor for further functionalization due to the presence of the aldehyde functionality, as well as a bioactive compound.
Tugba Taskin-Tok, Garkusha, N. A., Taskin-Tok, T., Safin, D. A., Damir A. Safin, Imren Bayıl, Nadezhda A. Garkusha, Bayıl, I., Anikeeva, O. P., Oksana P. Anikeeva   +9 more
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