SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation
Many essential proteins require pyridoxal 5’-phosphate, the active form of vitamin B6, as a cofactor for their activity. These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and ...
Izabella A. Pena +16 more
doaj +2 more sources
PYRIDOXAL-5'-PHOSPHATE INHIBITION OF PLATELET FUNCTION.
PYRIDOXAL-5'-PHOSPHATE INHIBITION OF PLATELET ...
ELIZABETH HARRIET. KORNECKI (7959149)
core +6 more sources
B6 vitamers as generators and scavengers of reactive oxygen species
B6 vitamers are important natural compounds for human life, principally for amino acid metabolism, and have been reported as potent scavenger molecules of both endogenous and exogenous reactive oxygen species (ROS).
Italo Rodrigo Calori +2 more
doaj +1 more source
Tumor metastasis is a major concern in cancer therapy. In this context, focal adhesion kinase (FAK) gene overexpression, which mediates cancer cell migration and invasion, has been reported in several human tumors and is considered a potential ...
Tilahun Ayane Debele +3 more
doaj +1 more source
Formation of a macrocycle from dichlorodimethylsilane and a pyridoxalimine Schiff base ligand
The reaction of dichlorodimethylsilane with a polydentate Schiff base ligand derived from pyridoxal and 2-ethanolamine yielded the macrocyclic silicon compound (8E,22E)-4,4,12,18,18,26-hexamethyl-3,5,17,19-tetraoxa-8,13,22,27-tetraaza-4,18-disilatricyclo[
Uwe Böhme +2 more
doaj +1 more source
(E)-4-(((2-amino-5-chlorophenyl)imino)methyl)-5-(hydroxy-methyl)-2-methylpyridin-3-ol and its Cu(II) complex: Synthesis, DFT calculations and AIM analysis [PDF]
Herein, (E)-4-{[(2-amino-5-chlorophenyl)imino]methyl}-5-(hydroxymethyl)- 2-methylpyridin-3-ol [HL] Schiff base and its [Cu(L)Cl] complex were newly synthesized and characterized by several spectroscopic methods.
Yavari Morteza +3 more
doaj +1 more source
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, G. +7 more
core +4 more sources
Pyridoxal in the Cerebrospinal Fluid May Be a Better Indicator of Vitamin B6–dependent Epilepsy Than Pyridoxal 5′-Phosphate [PDF]
Background We aimed to demonstrate the biochemical characteristics of vitamin B6–dependent epilepsy, with a particular focus on pyridoxal 5′-phosphate and pyridoxal in the cerebrospinal fluid. Methods Using our laboratory database, we identified patients
Ishihara, Naoko +19 more
core +2 more sources
Metal complexes with Schiff-base ligands - pyridoxal and semicarbazide-based derivatives [PDF]
The most important results of extensive studies (syntheses, spectral, magnetic, voltammetric and structural characteristics and biological activity) of metal complexes with pyridoxal semi-, thiosemi- and isothiosemicarbazones are reviewed.
VUKADIN M. LEOVAC +3 more
doaj +3 more sources
Pyridoxal Reductase, PdxI, Is Critical for Salvage of Pyridoxal in Escherichia coli
The biosynthetic pathway of pyridoxal 5′-phosphate (PLP) has extensively been studied in Escherichia coli, yet limited information is available about the vitamin B6 salvage pathway.
Tomokazu Ito, D. Downs
semanticscholar +1 more source

