Results 61 to 70 of about 48,907 (300)
Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor
ChemBioChem, EarlyView.This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau +3 more
wiley +1 more source
Ornithine decarboxylase activity, a clinical biomarker for evaluating cancer chemopreventive efficacy of phytomolecules [PDF]
, 2011 Biomarkers of cancer have made a strong traipse in predicting the disease pattern and contributed significantly to the understanding of tumour state, progression, characteristics and response to therapies.
Nusrat Masood +2 more
core +2 more sources
Molecules, 2020 Water-soluble vitamins like B3 (nicotinamide), B6 (pyridoxine), and B9 (folic acid) are of utmost importance in human health and disease, as they are involved in numerous critical metabolic reactions. Not surprisingly, deficiencies of these vitamins have
Ghada Rashad Ibrahim +5 more
doaj +1 more source
The intestine plays a substantial role in human vitamin B6 metabolism: a Caco-2 cell model. [PDF]
PLoS ONE, 2013 BACKGROUND: Vitamin B6 is present in various forms (vitamers) in the diet that need to be metabolized to pyridoxal phosphate (PLP), the active cofactor form of vitamin B6.
Monique Albersen +8 more
doaj +1 more source
Robust Artificial Polyenzyme for Recyclable Pickering Emulsion and Cascade Synthesis
ChemCatChem, EarlyView.Artificial polyenzyme (ArPoly) forms amphiphilic proteinpolymer conjugates that stabilize Pickering emulsions with tunable interfacial properties for biocatalysis. These emulsions enable efficient and robust single‐step reactions, multi‐step biocatalytic cascades, and whole‐cell catalysis.
Shan Wang, Changzhu Wu
wiley +1 more source
Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. [PDF]
PLoS ONE, 2012 Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms.
Amit K Gandhi +9 more
doaj +1 more source
Seminars in epileptology: How to diagnose status epilepticus in adults and children
Epileptic Disorders, EarlyView.Abstract Status epilepticus (SE) can be regarded as the most severe expression of seizure activity characterized by a low probability of spontaneous cessation and mechanisms leading to metabolic and inflammatory derangements with increased risk of brain damage, alterations of neural networks, and potentially life‐threatening systemic complications ...
M. Leitinger +12 more
wiley +1 more source
Metabolism of amino acid amides in Pseudomonas putida ATCC 12633 [PDF]
, 1993 The metabolism of the natural amino acid L-valine, the unnatural amino acids D-valine, and D-, L-phenylglycine (D-, L-PG), and the unnatural amino acid amides D-, L-phenylglycine amide (D, L-PG-NH2) and L-valine amide (L-Val-NH2) was studied in ...
Croes, L.M., +4 more
core +1 more source
Epileptic Disorders, EarlyView.Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor +7 more
wiley +1 more source
Journal of Laboratory Medicine, 2023 Concentrations of pyridoxal 5′-phosphate (PLP) in serum and whole blood are routinely measured. The suitability of these markers in capturing vitamin B6 insufficiency is not well studied.
Obeid Rima +2 more
doaj +1 more source