Results 31 to 40 of about 661,688 (260)

PDXK mutations cause polyneuropathy responsive to pyridoxal 5′‐phosphate supplementation

Annals of Neurology, 2019
To identify disease‐causing variants in autosomal recessive axonal polyneuropathy with optic atrophy and provide targeted replacement therapy.
V. Chelban, M. Wilson, J. Warman Chardon, J. Vandrovcova, M. N. Zanetti, E. Zamba-Papanicolaou, S. Efthymiou, S. Pope, M. Conte, Giancarlo Abis, Yo-Tsen Liu, Eloise Tribollet, Nourelhoda A. Haridy, J. Botía, M. Ryten, Paschalis Nicolaou, A. Minaidou, K. Christodoulou, K. Kernohan, Alison J Eaton, M. Osmond, Yoko A. Ito, P. Bourque, J. Jepson, O. Bello, F. Bremner, C. Cordivari, M. Reilly, M. Foiani, A. Heslegrave, H. Zetterberg, S. Heales, N. Wood, James E. Rothman, K. Boycott, P. Mills, P. Clayton, H. Houlden, Yamna Mohamed El Mhammed Stanislav Blagovesta Lionel Wol Kriouile Khorassani Aguennouz Groppa Marinova Kara, Y. Kriouile, M. Khorassani, M. Aguennouz, S. Groppa, Blagovesta Marinova Karashova, L. Van Maldergem, W. Nachbauer, S. Boesch, L. Arning, D. Timmann, B. Cormand, B. Pérez-Dueñas, G. Di Rosa, J. Goraya, T. Sultan, J. Mine, D. Avdjieva, H. Kathom, R. Tincheva, S. Banu, M. Pineda-Marfa, P. Veggiotti, Michel D. Ferrari, A. M. van den Maagdenberg, A. Verrotti, G. Marseglia, S. Savasta, M. García-Silva, A. M. Ruiz, Barbara H. Garavaglia, E. Borgione, S. Portaro, B. M. Sánchez, Richard S. Boles, S. Papacostas, M. Vikelis, James E. Rothman, P. Giunti, H. Houlden, V. Chelban, V. Salpietro, E. Oconnor, S. Efthymiou, D. Kullmann, R. Kaiyrzhanov, Roisin Sullivan, Alaa Khan, W. Y. Yau, I. Hostettler, E. Papanicolaou, E. Dardiotis, S. Maqbool, Shahnaz Ibrahim, S. Kirmani, N. Rana, Osama M Atawneh, Shen-Yang Lim, Farooq Shaikh, G. Koutsis, M. Breza, S. Mangano, C. Scuderi, Giovanna Morello, T. Stojkovic, E. Torti, M. Zollo, G. Heimer, Y. Dauvilliers, P. Striano, I. Al-Khawaja, Fuad Al-Mutairi, F. Alkuraya, Hamed Sherifa, M. Rizig, N. Okubadejo, O. Ojo, O. Oshinaike, K. Wahab, A. Bello, S. Abubakar, Yahaya O Obiabo, E. Nwazor, O. Ekenze, U. Williams, A. Iyagba, L. Taiwo, M. Komolafe, O. Oguntunde, S. Pchelina, Konstantin Senkevich, Nourelhoda A. Haridy, C. Shashkin, Nazira Zharkynbekova, Kairgali Koneyev, Ganieva Manizha, Maksudjon Isrofilov, Ulviyya Guliyeva, K. Salayev, Samson Khachatryan, S. Rossi, Gabriella Silvestri, Thomas Bourinaris, G. Xiromerisiou, L. Fidani, C. Spanaki, A. Tucci   +144 more
semanticscholar   +1 more source

Stability-indicating HPLC-PDA assay for simultaneous determination of paracetamol, thiamine and pyridoxal phosphate in tablet formulations

Acta Pharmaceutica, 2019
With the increased number of multi-drug formulations, there is a need to develop new methods for simultaneous determinations of drugs. A precise, accurate and reliable liquid chromatographic method was developed for simultaneous determination of ...
Ali Amir, Athar Muhammad Makshoof, Ahmed Mahmood, Nadeem Kashif, Murtaza Ghulam, Farooq Umar, Salman Muhammad   +6 more
doaj   +1 more source

Pyridoxal Phosphate vs Pyridoxine for Intractable Seizures

Pediatric Neurology Briefs, 2005
The efficacy of pyridoxal phosphate (PLP) compared to pyridoxine (PN) in the control of idiopathic intractable epilepsy was studied in 94 children, aged 8 months to 15 years, at the National Taiwan University Hospital, Taipei, Taiwan.
J Gordon Millichap
doaj   +1 more source

Labeling of hemoglobin with pyridoxal phosphate.

Journal of Biological Chemistry, 1982
The reaction of pyridoxal 5'-phosphate (PLP) with deoxyhemoglobin is confined to 2 residues in the beta chains, i.e. the alpha-amino group of valine 1 and the epsilon-amino group of lysine 82, both of which are located in the polyphosphate binding site.
James M. Manning, Ruth E. Benesch, A S Acharya, Suzanna Kwong, Reinhold Benesch   +4 more
openaire   +3 more sources

Structural Basis of the Substrate Specificity and Enzyme Catalysis of a Papaver somniferum Tyrosine Decarboxylase

Frontiers in Molecular Biosciences, 2017
Tyrosine decarboxylase (TyDC), a type II pyridoxal 5′-phosphate decarboxylase, catalyzes the decarboxylation of tyrosine. Due to a generally high sequence identity to other aromatic amino acid decarboxylases (AAADs), primary sequence information is not ...
Huai Guan, Huai Guan, Huai Guan, Shuaibao Song, Shuaibao Song, Shuaibao Song, Howard Robinson, Jing Liang, Haizhen Ding, Jianyong Li, Qian Han, Qian Han, Qian Han   +12 more
doaj   +1 more source

Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity. [PDF]

PLoS ONE, 2011
Despite intensive effort, the majority of the annotated Mycobacterium tuberculosis genome consists of genes encoding proteins of unknown or poorly understood function.
Ellene H Mashalidis, Tathagata Mukherjee, Paweł Sledź, Dijana Matak-Vinković, Helena Boshoff, Chris Abell, Clifton E Barry   +6 more
doaj   +1 more source

Cloning and Characterization of Pyridoxal Kinase from Geobacillus sp. H6a

Journal of Pure and Applied Microbiology, 2022
Pyridoxal kinase encoded by pdxK gene, is the important key enzyme in the salvage pathway of vitamin B6 biosynthesis. The enzyme catalyzes the phosphorylation of the 5′ alcohol groups of free form vitamin B6 into their 5′-phosphate forms that requires ...
Jumnong Pasri, Chamaiporn Champasri, Yanee Trongpanich   +2 more
doaj   +1 more source

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

Pteridines, 2002
Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography.
Rudzite Vera, Jurika Edite, Kalnins Uldis, Erglis Andrejs, Trusinskis Karlis, Jegere Sanda, Frick Barbara, Fuchs Dietmar   +7 more
doaj   +1 more source

Two-Photon Excited Fluorescence of NADH-Alcohol Dehydrogenase Complex in a Mixture with Bacterial Enzymes

Biomolecules, 2023
Thorough study of composition and fluorescence properties of a commercial reagent of active equine NAD-dependent alcohol dehydrogenase expressed and purified from E. coli has been carried out. Several experimental methods: spectral- and time-resolved two-
Ioanna A. Gorbunova, Maxim E. Sasin, Dmitry V. Yachkov, Denis A. Volkov, Alexei D. Vedyaykin, Andrey A. Nikiforov, Oleg S. Vasyutinskii   +6 more
doaj   +1 more source

Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.

PLoS ONE, 2019
L-aspartate aminotransferase is a pyridoxal 5'-phosphate-dependent transaminase that catalyzes reversible transfer of an α-amino group from aspartate to α-ketoglutarate or from glutamate to oxaloacetate.
Soo Yeon Jeong, Hyeonseok Jin, Jeong Ho Chang   +2 more
doaj   +1 more source