Results 61 to 70 of about 661,688 (260)

Micronutrient deficiencies after pancreatico‐duodenectomy: A narrative review of the literature and recommendations for clinical practice

Nutrition in Clinical Practice, EarlyView.
Abstract Micronutrient uptake is impaired after pancreatico‐duodenectomy (PD) because of malabsorption, reduced absorptive capacity, and poor oral intake. Biochemical depletion is reported in cohort studies, but deficiency states are predominantly reported in case reports, making it difficult to assess occurrence rates.
Mary E. Phillips, Callum Livingstone, Adam E. Frampton, Kathryn H. Hart   +3 more
wiley   +1 more source

Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5′-phosphate as the inhibitor

Journal of Lipid Research, 2006
Peroxidized phospholipid-mediated cytotoxity is involved in the pathophysiology of a number of diseases [i.e., the abnormal increase of phosphatidylcholine hydroperoxide (PCOOH) found in the plasma of type 2 diabetic patients]. The PCOOH accumulation may
Ohki Higuchi, Kiyotaka Nakagawa, Tsuyoshi Tsuzuki, Toshihide Suzuki, Shinichi Oikawa, Teruo Miyazawa   +5 more
doaj  

Variable treatment response in a patient with pyridoxal N phosphate oxidase (PNPO) deficiency- understanding the paradox

Epilepsy & Behavior Reports, 2020
A 6-year-old girl presented with history of infantile onset epileptic encephalopathy and developmental delay. She had polymorphic seizures that were refractory to regular anti-seizure medication.
Smilu Mohanlal, Parayil Sankaran Bindu, Sachin Sureshbabu, Suresh Kumar   +3 more
doaj  

Pyridoxal 5 phosphate for neuroleptic-induced tardive dyskinesia.

Cochrane Database of Systematic Reviews, 2015
BACKGROUND Tardive dyskinesia is a chronic and disabling abnormal movement disorder affecting the muscles of the face, neck, tongue and the limbs. It is a common side effect of long-term antipsychotic medication use in individuals with schizophrenia and ...
A. Adelufosi, O. Abayomi, Tunde Massey‐Ferguson Ojo   +2 more
semanticscholar   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

Pyrroloquinoline Quinone Is an Effective Senomorphic Agent to Target the Pro‐Inflammatory Phenotype of Senescent Cells

Aging Cell, EarlyView.
As a natural senomorphic agent, PQQ targets the intracellular molecule. HSPA8 of senescent cells, resulting in significantly reduced expression of the SASP. PQQ holds prominent potential to delay chronological aging and ameliorate age‐related conditions by acting as an effective senomorphic agent.
Birong Jiang, Hongwei Zhang, Qixia Xu, Zhirui Jiang, Ruikun He, Qiang Fu, Yu Sun   +6 more
wiley   +1 more source

Paradoxical Inhibition of Phosphorylase by Pyridoxal Phosphate [PDF]

Journal of Biological Chemistry, 1972
Abstract The reaction of phosphorylase b with pyridoxal-P results in partial inactivation of the enzyme and a change in enzymic characteristics. The reaction of enzyme with pyridoxal-P is reversible; it can be changed to an irreversible reaction by reduction of the pyridoxal-P-phosphorylase b complex with sodium borohydride.
Neil B. Madsen, Olga Avramovic-Zikic
openaire   +4 more sources

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Immediate-type hypersensitivity to pyridoxal 5'- phosphate: Study of in vivo and in vitro cross-reactivity and identification of the antigenic determinant

Allergology International, 2001
Background: A case in which a 45-year-old female patient with peritonitis experienced immediate-type hypersensitivity on two occasions after administration of preparations containing six different medications was referred to us for closer inspection ...
Masako Osada, Noriko Oki, Yukari Okubo, Tsunao Oh-i, Michiyuki Koga, Sadao Arai   +5 more
doaj   +1 more source

Characterization of gut microbiome composition in Iranian patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

Scientific Reports, 2023
Gut microbiota dysbiosis is intimately associated with development of non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).
Sara Abdollahiyan, Ali Nabavi-Rad, Shahrbanoo Keshavarz Azizi Raftar, Magali Monnoye, Naghmeh Salarieh, Azam Farahanie, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali, Behzad Hatami, Philippe Gérard, Abbas Yadegar   +10 more
doaj   +1 more source