Results 61 to 70 of about 40,643 (298)

Comparing the sensitivity of pyridoxal-5-phosphate, homocysteine and neopterin in coronary heart disease

open access: yesPteridines, 2002
Blood serum pyridoxal-5-phosphate, homocysteine and neopterin concentrations have been examined in 30 healthy individuals and 87 patients with coronary heart disease, verified by coronary angiography.
Rudzite Vera   +7 more
doaj   +1 more source

It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase. [PDF]

open access: yesPLoS ONE, 2011
The prevalent de novo biosynthetic pathway of vitamin B6 involves only two enzymes (Pdx1 and Pdx2) that form an ornate multisubunit complex functioning as a glutamine amidotransferase.
Cyril Moccand   +2 more
doaj   +1 more source

Pyridoxal Phosphate Supplementation in Neuropediatric Disorders

open access: yesSeminars in Pediatric Neurology, 2016
Pyridoxal phosphate (PLP) is the active form of vitamin B6 and a cofactor in many enzyme reactions including neurotransmitter metabolism. PLP metabolism disturbances may mostly lead to refractory seizures. In this report, we review the main pathophysiological factors related with PLP deficiency and our experience in PLP treatment in pediatric patients ...
Elisenda Cortès-Saladelafont   +4 more
openaire   +3 more sources

Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate

open access: yesScientific Reports, 2023
Pyridoxal-5′-phosphate (PLP) is a versatile cofactor that assists in different types of enzymatic reactions. PLP has also been reported to react with substrates and catalyze some of these reactions independent of enzymes.
Prajakatta Mulay   +2 more
doaj   +1 more source

The use of trade data in the analysis of global phosphate flows [PDF]

open access: yesarXiv, 2023
In this paper we present a new method to trace the flows of phosphate from the countries where it is mined to the countries where it is used in agricultural production. We achieve this by combining data on phosphate rock mining with data on fertilizer use and data on international trade of phosphate-related products.
arxiv  

Investigation of Structural Dynamics of Enzymes and Protonation States of Substrates Using Computational Tools. [PDF]

open access: yes, 2016
This review discusses the use of molecular modeling tools, together with existing experimental findings, to provide a complete atomic-level description of enzyme dynamics and function.
Chang, Chia-En A   +3 more
core   +2 more sources

Microbiome Single Cell Atlases Generated with a Commercial Instrument

open access: yesAdvanced Science, EarlyView.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li   +8 more
wiley   +1 more source

Glutamate in Pyridoxine-Dependent Epilepsy

open access: yesPediatric Neurology Briefs, 1994
Cerebrospinal fluid levels of glutamate, g-aminobutyric acid, and pyridoxal-5-phosphate examined in a patient with pyridoxine dependency while on and off vitamin B6 treatment are reported from Universitat Munchen, and Universitats-Nervenklinik, Wurzburg,
J Gordon Millichap
doaj   +1 more source

Metal binding to pyridoxal derivatives. An NMR study of the interaction of Eu(III) with pyridoxal phosphate and pyridoxamine phosphate [PDF]

open access: yes, 1979
The solution conformations of pyridoxal-5′-phosphate and pyridoxamine-5′-phosphate have been investigated using Eu(III) as a nuclear magnetic resonance shift probe.
Balaram, P.   +2 more
core   +1 more source

Update: Enzymatische Synthese für industrielle Anwendungen

open access: yesAngewandte Chemie, EarlyView.
Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer   +4 more
wiley   +1 more source

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