Results 71 to 80 of about 404,528 (235)
Reaction of Furanoeremophilans with Pyridoxal
Natural Product Communications, 2008 Furanoeremophilan-10β-ol, a major component of Ligularia cymbulifera growing in northwestern Yunnan Province of China, reacted with pyridoxal or its 5′-phosphate at room temperature in aqueous solution to afford condensation products.
Atsushi Torihata, Chiaki Kuroda
doaj +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila +5 more
wiley +1 more source
Structural insights into the orthosteric inhibition of P2X receptors by non-ATP analog antagonists
eLifeP2X receptors are extracellular ATP-gated ion channels that form homo- or heterotrimers and consist of seven subtypes. They are expressed in various tissues, including neuronal and nonneuronal cells, and play critical roles in physiological processes ...
Danqi Sheng +7 more
doaj +1 more source
Direct visualization of critical hydrogen atoms in a pyridoxal 5′-phosphate enzyme
Nature Communications, 2017 Pyridoxal 5’-phosphate (PLP) is a ubiquitous co factor for diverse enzymes, among them aspartate aminotransferase. Here the authors use neutron crystallography, which allows the visualization of the positions of hydrogen atoms, and computation to ...
Steven Dajnowicz +8 more
doaj +1 more source
Microbiota Medicine Research, EarlyView.Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi +7 more
wiley +1 more source
Microbiota Medicine Research, EarlyView.ABSTRACT Background Febrile infection‐related epilepsy syndrome (FIRES) is a catastrophic epileptic encephalopathy. Survivors often enter a chronic phase characterized by drug‐resistant epilepsy, cognitive impairment, behavioral and psychiatric symptoms, and long‐term functional disability.
Qianqian Li +3 more
wiley +1 more source
Natursown: the finely ground high-grade phosphate for heavy crops and permanent soil fertility. [PDF]
, 1916 Commercial booklet promoting the use of natural phosphate in agriculture.https://stars.library.ucf.edu/floridaheritage/1053/thumbnail ...
Lakeland Phosphate Company,
core
Hyperconjugation Promotes Catalysis in a Pyridoxal 5′-Phosphate-Dependent Enzyme
, 2018 Pyridoxal 5′-phosphate (PLP)-dependent enzymes facilitate reaction specificity by aligning the scissile σ-bond of the PLP-substrate covalent complex perpendicular to the ring of the cofactor.
Jerry M. Parks (1317393) +5 more
core +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The emergence of antibiotic resistance in bacteria is a major threat to global public health. To combat increasingly drug‐resistant bacteria like Pseudomonas aeruginosa, new targets for pharmaceuticals need to be explored. One such potential target for P.
Philipp Schneider +4 more
wiley +1 more source
Smart Molecules, EarlyView.Acidic pH triggers GOT1 phase separation via IDR1, recruiting ME1 to form ROS‐scavenging condensates that combat senescence, revealed by a FLIM‐based pH probe. Abstract Cellular senescence involves progressive acidification, but how cells sense and adapt to this pH shift remains unclear.
Ziyue Chen +8 more
wiley +1 more source