Quality and stability of extemporaneous pyridoxal phosphate preparations used in the treatment of paediatric epilepsy [PDF]
, 2017 Objectives To assess the pyridoxal 5′-phosphate (PLP) content and stability of extemporaneous PLP liquids prepared from dietary supplements used for the treatment of vitamin B6-dependent epilepsy.
Ting Chen +15 more
core +1 more source
Molecular Microbiology, EarlyView.Cellular pool of aromatic amino acid aminotransferase proteins represented as holo‐ or apo‐ enzymes, reflecting presence or absence of associated PLP. Status of PLPHP is implicated in determining the ratio of holo‐ and apo‐TyrB. ABSTRACT Pyridoxal 5′‐phosphate (PLP) is an essential cofactor required for metabolic functions including amino acid ...
Brandi A. Buckner, Diana M. Downs
wiley +1 more source
A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation
Angewandte Chemie, Volume 138, Issue 24, 8 June 2026.The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner +4 more
wiley +2 more sources
CNGCs in Marchantia paleacea uncouple arbuscular mycorrhizal symbiosis and rhizoid development
New Phytologist, EarlyView.Rhizoid growth and AM fungal infection are uncoupled. Summary In Marchantia paleacea, MpaDMI1‐dependent nuclear Ca2+ oscillations are essential for arbuscular mycorrhizal (AM) fungal colonisation, indicating that endosymbiosis‐mediated nuclear Ca2+ signalling is a conserved feature of land plant–AM symbiosis.
Anson Ho Ching Lam +3 more
wiley +1 more source
Proteomic and Phenotypic Analyses of a Putative YggS Family Pyridoxal Phosphate-Dependent Enzyme in Acidovorax citrulli. [PDF]
Plant Pathol J, 2023 Heo L +5 more
europepmc +1 more source
New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?
Oral Diseases, EarlyView.ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier +6 more
wiley +1 more source
Determination of pyridoxal phosphate and pyridoxal by the cyanohydrin method
Pyridoxal phosphate is a coenzyme in about 50 known enzymatic reactions. A simple and accurate method for the determination of pyridoxal phosphate would be desirable because it could provide a means to assess the nutritional status of vitamin B₆ in the ...
Chang, Susan Shao-Shu King
core
Plant Biotechnology Journal, EarlyView.ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang +12 more
wiley +1 more source
Multiplexed Assessment of Promiscuous Non-Canonical Amino Acid Synthase Activity in a Pyridoxal Phosphate-Dependent Protein Family. [PDF]
ACS Catal, 2023 Zmich A +4 more
europepmc +1 more source
Plants synthesize ergothioneine, showing a link to abiotic stress
Plant Biology, EarlyView.Various plants possess ergothioneine biosynthetic genes and can synthesize this antioxidant, where increased EGT levels under abiotic stress conditions indicate protective functions. Abstract Ergothioneine (EGT) is a sulphur‐containing histidine derivative and a potent antioxidant that exhibits beneficial effects on human health.
C. Kock +3 more
wiley +1 more source