MOLECULAR MECHANISMS UNDERLYING THERAPEUTIC ACTION OF VITAMIN B6
Фармация и фармакология (Пятигорск), 2023 The aim of the study was to analyze the molecular mechanisms that determine the possibility of using vitamin B6 in clinical practice for the correction of various pathological conditions.Materials and methods.
O. A. Zagubnaya, Y. R. Nartsissov
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GABA Synthesis and Pyridoxine Seizures
Pediatric Neurology Briefs, 1994 A reduction in pyridoxal-5-phosphate (PLP) dependent enzyme, glutamic acid decarboxylase (GAD),which synthesizes GABA, is reported in a 3 month-old infant with seizures responsive to pyridoxine treated at University of California, Davis.
J Gordon Millichap
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Assessment of vitamin E status in patients with systemic inflammatory response syndrome: plasma, plasma corrected for lipids or red blood cell measurements? [PDF]
, 2009 <b>Background:</b> There is some evidence that the plasma vitamin E status is perturbed as part of systemic inflammatory response and correcting this with other plasma markers may not lead to reliable results.
Duncan, A. +6 more
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First rare-earth phosphate aerogel: sol-gel synthesis of monolithic ceric hydrogen phosphate aerogel [PDF]
Journal of Sol-Gel Science and Technology 85 574-584 (2018), 2018 Since the late 1960s, ceric hydrogen phosphates have attracted the attention of scientists due to remarkable ion exchange, sorption, proton-conduction and catalytic properties. In this work, through the application of various solvents, we, for the first time, have obtained monolithic aerogels based on ceric hydrogen phosphates with high porosity (~99%)
arxiv +1 more source
Paradoxical Inhibition of Phosphorylase by Pyridoxal Phosphate [PDF]
Journal of Biological Chemistry, 1972 Abstract The reaction of phosphorylase b with pyridoxal-P results in partial inactivation of the enzyme and a change in enzymic characteristics. The reaction of enzyme with pyridoxal-P is reversible; it can be changed to an irreversible reaction by reduction of the pyridoxal-P-phosphorylase b complex with sodium borohydride.
Neil B. Madsen, Olga Avramovic-Zikic
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An Update: Enzymatic Synthesis for Industrial Applications
Angewandte Chemie International Edition, EarlyView.Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer +4 more
wiley +1 more source
The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]
, 2009 Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Carson, Ray J. +4 more
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yggS Encoding Pyridoxal 5′-Phosphate Binding Protein Is Required for Acidovorax citrulli Virulence
Frontiers in Microbiology, 2022 Bacterial fruit blotch, caused by seed-borne pathogen Acidovorax citrulli, poses a serious threat to the production of cucurbits globally. Although the disease can cause substantial economic losses, limited information is available about the molecular ...
Yuanjie Wang +9 more
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Functional Characterization of the Eukaryotic Cysteine Desulfurase Nfs1p from Saccharomyces cerevisiae [PDF]
, 2004 Previous studies have indicated that the essential protein Nfs1 performs a crucial role in cellular iron-sulfur (Fe/S) protein maturation. The protein is located predominantly in mitochondria, yet low amounts are present in cytosol and nucleus.
Balk +73 more
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Modification of Pepsinogen with Pyridoxal Phosphate
Journal of Biological Chemistry, 1974 Pyridoxal-PO4 binds to pepsinogen in a reaction in which the stoichiometry is highly dependent on the conformation of the protein. When pepsinogen is in its native conformation, pyridoxal-PO4 forms Schiff bases with the α-NH2 group of Leu1 and the e-NH2 group of Lys358.
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