Results 91 to 100 of about 28,846 (248)

Regorafenib‐Induced Hand‐Foot Skin Reaction in an Adolescent

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Regorafenib is a multikinase inhibitor commonly used in the management of hepatocellular carcinoma, gastrointestinal stromal tumors (GIST), and colorectal cancer. It is also used off‐label for progressive or metastatic osteosarcoma, which is the most common primary bone malignancy in children and adolescents.
Kiera Murphy   +3 more
wiley   +1 more source

Pyridoxamine does not reduce arterial stiffness in an 8‐week randomized double‐blind placebo‐controlled intervention trial with abdominally obese individuals

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Mathias D. G. Van den Eynde   +8 more
wiley   +1 more source

The Landscape of Cancer Metabolism as a Therapeutic Target

open access: yesPathology International, EarlyView.
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

open access: yesExperimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng   +1 more
wiley   +1 more source

Effectiveness of Pyridoxal‐5′‐Phosphate in PNPO Deficiency: A Systematic Review

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.
ABSTRACT Pyridox(am)ine 5′‐phosphate oxidase (PNPO) deficiency is an ultrarare inherited neurometabolic disease, characterized by primarily neonatal‐onset B6‐responsive epileptic encephalopathies. Treatment often requires sustainable access to high‐quality pyridoxal‐5′‐phosphate (PLP, i.e., active vitamin B6), although some patients (also) respond to ...
Nina N. Stolwijk   +7 more
wiley   +1 more source

The Influence of Ethanolic Extract of Hypericum Perforatum (St. John's wort) on Growth Performance, Serum Metabolites, Fat Deposition, Immunity, and Lipid Peroxidation in Broiler Chickens

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
ABSTRACT Background Having bioactive components such as hypericin, hyperforin and quercetin has enabled Hypericum perforatum (HP) to show antioxidant, antiviral and hypocholesterolemic effects in different animal species. Objectives This study aimed to investigate the effects of different levels of Hypericum perforatum extract (HPE) additions on ...
Mohammad Ali Behroozilak   +4 more
wiley   +1 more source

Features and Prognosis of Patients With Retroperitoneal Fibrosis Developing Fibrosing Mediastinitis: Case‐Control Study and Systematic Review

open access: yesACR Open Rheumatology, Volume 7, Issue 8, August 2025.
Objective Retroperitoneal fibrosis (RPF) complicated by mediastinal fibrosis (MF) is rare but fatal. We aimed to explore the features and indicators of poor prognosis for the population of those affected. Methods Patients with idiopathic RPF were recruited in Peking University International Hospital.
Yishan Ding   +8 more
wiley   +1 more source

Growth Performance of Atlantic Salmon Smolts Fed Diets Containing Three Levels of a Single Cell Protein, Torula Yeast

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 4, August 2025.
The use of alternative proteins ingredients is needed to support aquaculture. Yeast cells, a single cell protein ingredient, can be successfully incorporated into Atlantic salmon diets without affecting growth performance. ABSTRACT Atlantic salmon (Salmo salar) are globally cultured fish that are typically fed high protein and high lipid diets ...
Brian C. Peterson   +3 more
wiley   +1 more source

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