Results 131 to 140 of about 66,485 (345)
Status epilepticus in older adults: A critical review
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward+5 more
wiley +1 more source
Pyridoxine responsive epilepsy caused by a novel homozygous PNPO mutation
We report a patient with anti-epileptic treatment refractory neonatal seizures responsive to pyridoxine. Biochemical analysis revealed normal markers for antiquitin deficiency and also mutation analysis of the ALDH7A1 (Antiquitin) gene was negative ...
B. Jaeger+6 more
doaj +1 more source
A COMPARISON OF THE EFFECTS OF PYRIDOXINE AND PANTOTHENIC ACID DEFICIENCIES ON THE NERVOUS TISSUES OF SWINE [PDF]
Richard H. Follis, M. M. Wintrobe
openalex +1 more source
First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi+15 more
wiley +1 more source
Antidote Stocking at Hospitals in North Palestine [PDF]
Objective: The purpose of this study was to determine the availability and adequacy of antidote stocking at hospitals in north Palestine based on published guidelines for antidote stocking.
Al-Jabi W, Samah+3 more
core +1 more source
Cystathionine β‐synthase (CBS) is an essential enzyme involved in cysteine metabolism. The mutation R336C, associated with severe homocystinuria and of high incidence in Qatar, reduces its activity. Our research shows that this mutation does not destabilize the enzyme fold but subtly alters the tautomeric equilibrium of the PLP cofactor within the ...
Carolina Conter+10 more
wiley +1 more source
Aquaculture Asia, Vol. 10, No. 1, pp.1-50, January - March 2005 [PDF]
CONTENTS: Freshwater prawn culture in China and its market prospects, by Miao Weimin. Demise of wastewater-fed duckweed based aquaculture in Bangladesh, by Peter Edwards.
core
Here, we generated a DDC‐KO cellular model for studying aromatic amino acid decarboxylase (AADC) deficiency. This model was created using CRISPR‐Cas9 in the SH‐SY5Y neuroblastoma cell line and was validated through the absence of the dopamine product and an altered l‐dopa metabolite profile.
Cristian Andres Carmona‐Carmona+11 more
wiley +1 more source
SORPTION ISOTHERM OF PYRIDOXINE HYDROCHLORIDE ON GLAUCONITE
Natural aluminosilicates are promising sorbents that can be used to separate and isolate biologically active substances, namely vitamins. Hydrochloride pyridoxine (vitamin B6) is an important biologically active compound necessary for the normal ...
Kotova Diana L.+4 more
doaj +1 more source
Old player, new roles: defining the role of the plastidial phosphorylase
Summary The plastidial phosphorylase (Pho1 or Phs1; E.C. 2.4.1.1) is a ubiquitous enzyme among plants that catalyzes the formation and degradation of glucans. Although the first report connecting Pho1 with starch metabolism came out > 80 years ago, its precise role is still a matter of debate.
David Seung+2 more
wiley +1 more source