Results 31 to 40 of about 33,290 (259)
Pyridoxine for prevention and treatment of PARP inhibitor induced nausea and vomiting
Poly-ADP ribose polymerase inhibitors (PARPi) are a promising new treatment option for patients with ovarian cancer and are moderately emetogenic. Tolerance of therapy is paramount, and uncontrolled nausea and vomiting may limit use.
Stuart A. Ostby +2 more
doaj +1 more source
Pyridoxine, one of the vitamin B6 vitamers, plays a crucial role in amino acid metabolism and synthesis of monoamines as a cofactor. In the present study, we observed the effects of pyridoxine deficiency on novel object recognition memory.
Hyo Young Jung +9 more
doaj +1 more source
Title: Reactions of Pyridoxine, Author: Frederick J. Rowell, Location: ThodeThe chemistry of pyridoxine has been critically examined with a view to obtaining new intermediates suitable for the systematic degradation of the molecule.
Rowell, Frederick J.
core +1 more source
Pyridoxine hydrochloride is a form of vitamin B6, an essential micronutrient. It occurs in the body as pyridoxal 5’‐phosphate. It serves as a coenzyme in transamination, decarboxylation and desamination reactions.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj +1 more source
Background: Vascular diseases are multifactorial and several risk factors may have synergetic effect on the global vascular risk. Among patients with diabetes, we investigated whether vitamin B6 species differ according to global cardiovascular risk ...
Rima Obeid +2 more
doaj +1 more source
Glutamate carboxypeptidase II inhibition behaviorally and physiologically improves pyridoxine-induced neuropathy in rats. [PDF]
Pyridoxine is used as a supplement for treating conditions such as vitamin deficiency as well as neurological disorders such as depression, epilepsy and autism.
Michelle C Potter +3 more
doaj +1 more source
Comparing between Pyridoxine hydrochloride, Doxylamine Succinate/Pyridoxine Hydrochloride and Ondansetron for Treatment of Nausea and Vomiting in Pregnant Females [PDF]
Background: Nausea and vomiting of pregnancy (NVP) is a common gestational condition, NVP affecting up to 80% of the pregnant women and are the third leading causes of maternal hospitalization during pregnancy.
taghreed farahat +4 more
doaj +1 more source
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li +9 more
wiley +1 more source
A 6-year-old girl presented with history of infantile onset epileptic encephalopathy and developmental delay. She had polymorphic seizures that were refractory to regular anti-seizure medication.
Smilu Mohanlal +3 more
doaj +1 more source
Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis
Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko +8 more
wiley +1 more source

