Results 21 to 30 of about 6,810 (200)

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

An IscS Persulfide Donates the Sulfur for Ribosomal Protein uL16 Thioamidation

open access: yesAngewandte Chemie, EarlyView.
YcaO‐catalyzed thioamidation of the ribosomal subunit protein uL16 is widespread in Pseudomonadota bacteria. We identify the iron–sulfur cluster cysteine desulfurase IscS as the sulfur donor via an IscS persulfide and observe direct IscS–uL16 interactions.
Yanqing Xue   +2 more
wiley   +2 more sources

Pyridoxine-Dependent Epilepsy and Antiquitin Deficiency Resulting in Neonatal-Onset Refractory Seizures

open access: yesBrain Sciences, 2021
Pyridoxine-dependent epilepsy (PDE) is an autosomal recessive neurometabolic disorder due to a deficiency of α-aminoadipic semialdehyde dehydrogenase (mutation in ALDH7A1 gene), more commonly known as antiquitin (ATQ).
Konrad Kaminiów   +3 more
doaj   +1 more source

Hematologic Response of Pyridoxine Deficient Swine to Pyridoxine.

open access: yesExperimental Biology and Medicine, 1963
SummaryThe anemia of pyridoxine-deficient swine fed a purified diet with 10 crystalline water soluble vitamins responded rapidly and completely to administration of pyridoxine. The mean volume of packed red cells (V. P. R. C.) at the beginning of the experiment was 40 ml/100 ml; at time of therapy, 23 ml/100 ml; and after therapy with pyridoxine, 41 ml/
G E, CARTWRIGHT, D, KURTH, M M, WINTROBE
openaire   +2 more sources

Pyridoxine for prevention and treatment of PARP inhibitor induced nausea and vomiting

open access: yesGynecologic Oncology Reports, 2019
Poly-ADP ribose polymerase inhibitors (PARPi) are a promising new treatment option for patients with ovarian cancer and are moderately emetogenic. Tolerance of therapy is paramount, and uncontrolled nausea and vomiting may limit use.
Stuart A. Ostby   +2 more
doaj   +1 more source

Reactions of Pyridoxine [PDF]

open access: yes, 1970
Title: Reactions of Pyridoxine, Author: Frederick J. Rowell, Location: ThodeThe chemistry of pyridoxine has been critically examined with a view to obtaining new intermediates suitable for the systematic degradation of the molecule.
Rowell, Frederick J.
core   +1 more source

Effects of Pyridoxine Deficiency on Hippocampal Function and Its Possible Association with V-Type Proton ATPase Subunit B2 and Heat Shock Cognate Protein 70

open access: yesCells, 2020
Pyridoxine, one of the vitamin B6 vitamers, plays a crucial role in amino acid metabolism and synthesis of monoamines as a cofactor. In the present study, we observed the effects of pyridoxine deficiency on novel object recognition memory.
Hyo Young Jung   +9 more
doaj   +1 more source

Treatable cause of refractory seizures in an infant with a novel mutation

open access: yesJournal of Pediatric Neurosciences, 2021
Pyridoxine-dependent epilepsy is a treatable cause of epilepsy, which is very well known. It is most commonly caused by mutations in ALDH7A1 and PNPO genes. A 5-month-old infant presented with refractory seizures.
Ruchi R Mittal   +2 more
doaj   +1 more source

Amplitude-integrated encephalography in pyridoxine-dependent seizures and pyridoxine-responsive seizures.

open access: yes, 2002
Pyridoxine-dependent seizures are rare in newborn infants, although recent data suggest that the prevalence probably is underestimated. In all newborn infants with recurrent epileptic seizures the general recommendation is to administer pyridoxine and ...
Hellström-Westas, Lena   +9 more
core   +1 more source

Scientific Opinion on the safety and efficacy of vitamin B6 as a feed additive for all animal species

open access: yesEFSA Journal, 2010
Pyridoxine hydrochloride is a form of vitamin B6, an essential micronutrient. It occurs in the body as pyridoxal 5’‐phosphate. It serves as a coenzyme in transamination, decarboxylation and desamination reactions.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

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