Results 11 to 20 of about 36,321 (324)

Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H + -driven lysosomal pyridoxine exporter

Life Science Alliance, 2023
DIRC2 is an H + -driven lysosomal pyridoxine exporter involved in the regulation of cellular pyridoxine storage. Disrupted in renal carcinoma 2 (DIRC2) has gained interest because of its association with the development of renal cancer and cosegregation ...
Shogo Akino, Tomoya Yasujima, Takahiro Yamashiro, Hiroaki Yuasa   +3 more
doaj   +1 more source

Beta-nerve growth factor gene therapy alleviates pyridoxine-induced neuropathic damage by increasing doublecortin and tyrosine kinase A in the dorsal root ganglion

Neural Regeneration Research, 2020
Beta-nerve growth factor (β-NGF) is known to be a major leading cause of neuronal plasticity. To identify the possible action mechanisms of β-NGF gene therapy for sciatic nerve recovery, experimental dogs were randomly divided into control, pyridoxine ...
Hyun-Kee Cho, Woosuk Kim, Kwon-Young Lee, Jin-Ok Ahn, Jung Hoon Choi, In Koo Hwang, Jin-Young Chung   +6 more
doaj   +1 more source

8-Way Randomized Controlled Trial of Doxylamine, Pyridoxine and Dicyclomine for Nausea and Vomiting during Pregnancy: Restoration of Unpublished Information. [PDF]

PLoS ONE, 2017
OBJECTIVESWe report information about an unpublished 1970s study ("8-way" Bendectin Study) that aimed to evaluate the relative therapeutic efficacy of doxylamine, pyridoxine, and dicyclomine in the management of nausea and vomiting during pregnancy.
Rujun Zhang, Navindra Persaud
doaj   +1 more source

Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency) [PDF]

, 2010
Pyridoxine-dependent epilepsy was recently shown to be due to mutations in the ALDH7A1 gene, which encodes antiquitin, an enzyme that catalyses the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-{alpha}-aminoadipic semialdehyde/L-{Delta}
Hemingway, Cheryl, François Feillet, Pascale De Lonlay, Sarah Aylett, Struys, E A, Dulac, Olivier, Schmitt, Bernhard, Bernhard Schmitt, Jakobs, C, Rennie, J, Marlow, N., Hughes, M. I., De Lonlay, Pascale, Pike, M G, Mills, P B, Dulac, O, Feillet, François, Zuberi, S. M., Eduard A. Struys, Mills, Kevin A, William J. Craigen, Christensen, Ernst, Schmitt, B, De Lonlay, P, Footitt, E. J., Janet Rennie, Christensen, E., Emma J. Footitt, Tuschl, Karin, Struys, E. A., Hemingway, C., Mills, P.B., Marlow, N, Baxter, P, Footitt, E.J., Hughes, M Imelda, Aylett, S, De Lonlay, P., Rennie, Janet, Mills, K.A., Sameer M. Zuberi, Mills, K A, Struys, Eduard A, Lonlay, P. de, Tuschl, K, Varadkar, S, Rima Nabbout, Karin Tuschl, Aylett, Sarah, Clayton, P. T., Varadkar, Sophia, Philippa B. Mills, Footitt, E J, Zuberi, S M, Ernst Christensen, Aylett, S., Peter Baxter, Clayton, Peter T, Zuberi, S.M., Neil Marlow, Peter T. Clayton, M. Imelda Hughes, Jakobs, Cornelis, Pike, M.G., Tuschl, K., Hughes, M.I., Schmitt, B., Baxter, P., Clayton, P T, Sophia Varadkar, Struijs, E.A., Craigen, W J, Footitt, Emma J, Feillet, F., Cheryl Hemingway, Hughes, M I, Craigen, W.J., Dulac, O., Nabbout, Rima, Pike, M. G., Mike G. Pike, Feillet, F, Pike, Mike G, Rennie, J., Mills, P. B., Christensen, E, Marlow, Neil, Kevin A. Mills, Olivier Dulac, Zuberi, Sameer M, Craigen, William J, Nabbout, R, Mills, K. A., Varadkar, S., Baxter, Peter, Mills, Philippa B, Nabbout, R., Clayton, P.T., Jakobs, C., Hemingway, C, Cornelis Jakobs, Craigen, W. J.   +101 more
core   +1 more source

USE OF PYRIDOXINE TO INCREASE ANTICACNER ACTIVITY OF METHIONINE-GAMMA-LYASE IN MURINE CANCER MODELS

Сибирский онкологический журнал, 2017
We presented results of monotherapy and combination therapy of transplantable murine tumor models using methionine-gamma-lyase (MGL) and pyridoxine hydrochloride. We studied MGL from Clostridium sporogenes and Citrobacter freundii.
D. Zh. Davydov, Е. А. Morozova, М. V. Komarova, N. V. Anufrieva, G. B. Zavilgelsky, I. V. Manukhov, T. V. Demidkina, Е. М. Treshchalina, V. S. Pokrovsky   +8 more
doaj   +1 more source

Pyridoxine‐responsive KCNQ2 epileptic encephalopathy: Additional cases and literature review

Molecular Genetics & Genomic Medicine, 2022
Background Typical patients with KCNQ2 (OMIM# 602235) epileptic encephalopathy present early neonatal‐onset intractable seizures with a burst suppression EEG pattern and severe developmental delay or regression, and those patients always fail first‐line ...
Jun Chen, Qiuji Tao, Lijuan Fan, Yajun Shen, Jinfeng Liu, Huan Luo, Zuozhen Yang, Mengmeng Liang, Jing Gan   +8 more
doaj   +1 more source

A Case of Pyridoxine Dependent Epilepsy Presented with Status Epilepticus [PDF]

, 2019
Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive encephalopathy due to mutations in the ALDH7A1 gene. Intractable seizures are the most frequent clinical form in the early infantile period.
Hamide Betül Gerik Çelebi, Senem Ayça, Sırrı Çam, Muzaffer Polat   +3 more
core   +1 more source

Study of Boron Complexation with Pyridoxine: Effect of Interaction Time, Temperature, and Amount of Pyridoxine

, 2023
Borax is one of the compounds of boron (B), which is widely used as an anti-fungal, wood preservative, and antiseptic in cosmetics. Boron can form complexes with biomolecules such as pyridoxine, so it is interesting to know the interaction between borax ...
Nurlisa Hidayati, Hidayati, Nurlisa, Arnela, Mita, Ariqah Fianti, Fianti, Ariqah, Mita Arnela   +5 more
core   +1 more source

Pyridoxine: The ‘Ba.Six’ of use in Nausea and Vomiting of Pregnancy [PDF]

Journal of Clinical and Diagnostic Research, 2019
Over the centuries, the dietary and biochemical essentiality of pyridoxine in the humans has been well established. Apart from various physiological functions, pyridoxine is therapeutically important in Nausea and Vomiting of Pregnancy (NVP).
Abbas Hassan, Arun Kumar Dubey, Malpe Surekha Bhat   +2 more
doaj   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo-Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men. [PDF]

Adv Sci (Weinh)
Højfeldt G, Michaud J, Damgaard A, Karlog K, Migliavacca E, Karaz S, Pazirandeh-Micol E, Johansen OE, Karagounis LG, Helge BW, Hagemann W, Kjaer M, Feige JN, Stuelsatz P, Mackey AL.   +14 more
europepmc   +2 more sources