Results 61 to 70 of about 28,846 (248)

Pyridoxine for prevention of hand-foot syndrome caused by chemotherapy: a systematic review.

open access: yesPLoS ONE, 2013
BackgroundHand-foot syndrome (HFS) is a relatively frequent dermatologic toxic reaction to certain anti-cancer chemotherapies. The syndrome can evolve into a distressing condition that limits function and affects quality of life.
Min Chen   +3 more
doaj   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

MORPHOFUNCTIONAL CHARACTERISTICS OF FIBROBLASTS (MCCOY CELL LINE) CULTURED WITH MAGNESIUM PREPARATIONS

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To study the effect of magnesium orotate, magnesium/pyridoxine combination and magnesium sulfate on fibroblast morphofunctional characteristics in cell culture of fibroblasts (McCoy line).Material and methods.
L. V. Didenko   +5 more
doaj   +1 more source

Red cell aspartate aminotransferase saturation with oral pyridoxine intake

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: The coenzyme of aspartate aminotransferase is pyridoxal phosphate, generated from fresh vegetables containing pyridoxine. Vitamin B6-responsive sideroblastic anemia, myelofibrosis and Peyronie’s syndrome respond to high pyridoxine ...
Marilena Oshiro   +3 more
doaj   +1 more source

Effect of 3‐mercaptopyruvate sulfurtransferase (3‐MST) inhibitors on contractile responses in porcine coronary artery

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β‐synthase (CBS), cystathionine γ‐lyase (CSE) and 3‐mercaptopyruvate sulfurtransferase (3‐MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3‐MST is unknown. In this study, we demonstrate the effect
Maha Almaheize   +7 more
wiley   +1 more source

Properties of Pyridoxine Glucoside

open access: yesTHE JOURNAL OF VITAMINOLOGY, 1971
Intact pyridoxine glucoside showed about 20% of microbiological activity of equivalent mole of pyridoxine for Saccharomyces carlsbergensis 4228 ATCC 9080. The activity was gradually increased accompanied with the prolonged incubation. It seems that pyridoxine glucoside is hydrolyzed to pyridoxine and glucose by α-glucosidase of Saccharomyces ...
Koichi Ogata   +2 more
openaire   +4 more sources

Levodopa‐Responsive Dystonia Secondary to CTNNB1 Neurodevelopmental Disorder

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Hanin Algethami   +5 more
wiley   +1 more source

Coloured polyhydroxyalkanoates: A review

open access: yesColoration Technology, EarlyView.
Abstract Polyhydroxyalkanoates (PHAs) are a class of biopolymers produced by various microorganisms, with poly(3‐hydroxybutyrate) being the most extensively studied. PHAs are widely studied as substitutes for conventional plastics due to their similar physicochemical properties. However, the production cost of PHAs remains high.
Maria Luiza de Oliveira Zanini   +3 more
wiley   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment. The pathogenesis of these lesions encompasses a range of causes, including haemorrhagic, embolic, or other vascular events; exposure to teratogens, such as drugs or substance
Ana Alarcón   +33 more
wiley   +1 more source

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