Results 71 to 80 of about 28,846 (248)

Pyridoxine Dependent Seizures-Report Of A Case And Brief Review Of Literature

open access: yesAnnals of Indian Academy of Neurology, 2002
Pyridoxine-dependent seizure is a rare autosornal recessive disorder that usually presents as neonatal intractable seizures. This syndrome is due to an inborn abnormality of the enzyme glutamic acid decarboxylase, which results in reduced pyridoxine ...
Rajesh R, Girija AS
doaj  

Spectroelectrochemical Investigation of the Interaction of Adenine with Pyridoxine at Physiological pH

open access: yesJournal of Spectroscopy, 2019
Spectroelectrochemical techniques were used to probe the interaction of adenine with pyridoxine at pH 7.0. Analysis of UV-visible absorption of the adenine-pyridoxine complex at 260 nm using the Lineweaver–Burk double reciprocal plot produced a linear ...
Yasmin Roye   +3 more
doaj   +1 more source

Variable treatment response in a patient with pyridoxal N phosphate oxidase (PNPO) deficiency- understanding the paradox

open access: yesEpilepsy & Behavior Reports, 2020
A 6-year-old girl presented with history of infantile onset epileptic encephalopathy and developmental delay. She had polymorphic seizures that were refractory to regular anti-seizure medication.
Smilu Mohanlal   +3 more
doaj  

Does pyridoxine control behavioral symptoms in adult patients treated with levetiracetam? Case series from UAE

open access: yesEpilepsy and Behavior Case Reports, 2015
Behavioral symptoms are known side effects of levetiracetam. Previous case series in children and adolescents have demonstrated the potential effect of pyridoxine in ameliorating these symptoms.
Taoufik Alsaadi   +2 more
doaj   +1 more source

Higher plasma dicarbonyl levels are associated with liver fibrosis in obese individuals

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Introduction Methylglyoxal (MGO) is a very reactive compound that modifies proteins, forming advanced glycation end products (AGEs) and activating inflammatory pathways. Elevated MGO levels have been linked to various diseases, including type 2 diabetes and atherosclerosis. However, the role of MGO and other glycating agents in the progression
Oluwatomisono I. Akinrimisi   +12 more
wiley   +1 more source

Status epilepticus in older adults: A critical review

open access: yesEpilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward   +5 more
wiley   +1 more source

First‐in‐class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus

open access: yesThe FEBS Journal, EarlyView.
The production of the iron‐chelating compound staphyloferrin B by the most invasive S. aureus strains is crucial for colonization, virulence, and survival in the host. Staphyloferrin B biosynthesis is carried out by eight enzymes, the Sbn system, that offer an appealing source of potential targets for the development of antimicrobials.
Sarah Hijazi   +15 more
wiley   +1 more source

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