Results 71 to 80 of about 34,811 (248)
A 66‐year‐old man with acute retinal necrosis
Brain Pathology, EarlyView.
Shino Magaki +3 more
wiley +1 more source
Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]
Iranian Journal of Public Health, 2008 Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi +5 more
doaj +1 more source
Improved synchronous production of Plasmodium falciparum gametocytes in vitro.
, 2007 The sexual stages of the Plasmodium falciparum life cycle are attractive targets for vaccines and transmission blocking drugs. Difficulties in culturing and obtaining large amounts of sexual stage P.
Baker, David A +7 more
core +1 more source
Effectiveness of intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) in Ghana [PDF]
, 2021 David Dosoo +12 more
openalex +1 more source
Malaria Journal, 2004 The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille +2 more
doaj +1 more source
Aggregate, Volume 6, Issue 12, December 2025.A bacterial DNA‐targeted PS TPE‐CN for the precise treatment of MRSA‐associated infections has been developed. Through synergistic PDT effect, TPE‐CN damages bacterial DNA and membrane, resulting in effective elimination of planktonic bacteria, biofilm, and intracellular bacteria.
Yonghui Lv +7 more
wiley +1 more source
Ein neuer Malariawirkstoff hemmt die Proteinsynthese von Plasmodium falciparum
Angewandte Chemie, Volume 137, Issue 49, December 1, 2025.Die Verbindung 31 stellt einen vielversprechenden Ansatz für die Entwicklung eines Malariawirkstoffs mit einem starken Wirkungsprofil dar (PfNF54 IC50 ± s.d. = 3,9 ± 0,4 nM). Sie hat einen neuartigen Wirkmechanismus, indem sie an zytosolische Ribosomen‐Untereinheiten bindet und dadurch die Proteinsynthese im Parasiten hemmt.
Patricia Bravo +16 more
wiley +1 more source
, 2008 Buffet and colleagues have reviewed some of the potential benefits and drawbacks of intermittent preventive antimalarial treatment in children (IPTc).
Bojang, Kalifa +5 more
core +1 more source
Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]
, 2012 Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund +2 more
core +2 more sources
A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum
Angewandte Chemie International Edition, Volume 64, Issue 49, December 1, 2025.Compound 31 represents a promising avenue for the development as an antimalarial agent with a potent activity profile (PfNF54 IC50 ± s.d. = 3.9 ± 0.4 nM). It has a novel mode of action by binding to cytosolic ribosomal subunits, thereby inhibiting protein synthesis in the parasite.
Patricia Bravo +16 more
wiley +1 more source