Pyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream forms. [PDF]
PLoS ONE, 2013 BackgroundAfrican trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.Methodology/principal findingsPyrimidine requirements for
Juma A M Ali +5 more
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13C n.m.r. investigation on the nitrogen methylation of some azabenzenes [PDF]
, 1977 The 1H and 13C n.m.r. spectra of N-methylated pyridine, pyridazine, pyrimidine and pyrazine and N,N-dimethylated pyrimidine and pyrazine have been recorded and analysed.
Mohan, Chandra, Weijer, Peter van de
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Phosphorylation of purine and pyrimidine nucleosides by isolated rat liver mitochondria [PDF]
, 1975 Formation of 5'-AMP, 5'-GMP, 5'-CMP and 5'UMP was confirmed in isolated rat liver mitochondria incubated with alpha-ketoglutarate, inorganic phosphate, purine nucleoside and pyrimidine nucleoside. Increased incorporation of 32Pi into ATP, GTP and UTP was
Inaba, Kozo, Oda, Takuzo
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N—H⋯N hydrogen bonding in 4,6-diphenyl-2-pyrimidinylamine isolated from the plant Justicia secunda (Acanthaceae) [PDF]
, 2004 The title compound, C₁₆H₁₃N₃, isolated from Justicia secunda (Acanthaceae), comprises two molecules (which differ slightly in conformation) in the asymmetric unit of space group P\overline 1.
Chatterjee, Baidyanath +4 more
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Molecules, 2020 This work demonstrates synthetic strategies for the incorporation of a synthesized pyrimidine glucagon-like peptide-1 (GLP-1) agonist into alginate-coated ZIF-8.
Shaikha S. AlNeyadi +6 more
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Bimetallic Pt(II)-bipyridyl-diacetylide/Ln(III) tris-diketonate adducts based on a combination of coordinate bonding and hydrogen bonding between the metal fragments: syntheses, structures and photophysical properties [PDF]
, 2009 The luminescent Pt(II) complex [Pt(4,4'-Bu-t(2)-bipy){CC-(5-pyrimidinyl)}(2)] (1) was prepared by coupling of [Pt(4,4'-Bu-t(2)-bipy)Cl-2] with 5-ethynyl-pyrimidine, and contains two pyrimidinyl units pendant from a Pt(H) bipyridyl diacetylide core; it ...
Beeby +30 more
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Chemical Insights Into the Synthetic Chemistry of Quinazolines: Recent Advances
Frontiers in Chemistry, 2021 In medicinal chemistry, one of the most significant heterocyclic compounds are quinazolines, possessing broad range of biological properties such as anti-bacterial, anti-fungal, anti-HIV, anti-cancer, anti-inflammatory, and analgesic potencies.
Muhammad Faisal, Aamer Saeed
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Synthesis and coordination chemistry of 2-(di-2-pyridylamino)pyrimidine; structural aspects of spin crossover in an Fe(II) complex [PDF]
, 2012 This paper was accepted on February 26 20122-(Di-2-pyridylamino)pyrimidine (L), a potentially ditopic tetradentate ligand, was synthesized from commercially available di-2-pyridylamine and 2-chloropyrimidine.
Addison +38 more
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1-Methyl-4-phenyl-1H-pyrazolo[3,4-d]pyrimidine
IUCrData, 2017 In the crystal, molecules of the title compound, C12H10N4, stack in a head-to-tail manner along the b direction through π–π stacking interactions between both portions of the pyrazolopyrimidine ring system.
Mohamed El Hafi +5 more
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The Effects of Ultraviolet Light on Anthocyanin Accumulation in the Adventitious Roots of Sedum wrightii (Crassulaceae) [PDF]
, 2018 Several studies have supported the idea that anthocyanin accumulation may be a possible protection mechanism in plants against DNA damage caused by ultraviolet radiation (UV).
Gravatt, Dennis A. +2 more
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