Results 271 to 280 of about 314,968 (285)

DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.

Org Biomol Chem
Nieuwland C, van Well MJ, Guillaumes L, de Vey Mestdagh A, Dekker L, Nieuweboer C, Simon S, Fonseca Guerra C.   +7 more
europepmc   +1 more source

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Structure-Activity Relationships of Pyrimidine Derivatives and Their Biological Activity - A Review.

Medicinal chemistry, 2022
BACKGROUND Heterocycles are a major role in many fields of biochemical and physiological such as amino acids, DNA bases, vitamins, endogenous neurotransmitters, etc.
Ramalakshmi Natarajan, Helina N, A. S, A. S   +3 more
semanticscholar   +1 more source

Pyrimidine: An elite heterocyclic leitmotif in drug discovery‐synthesis and biological activity

Chemical Biology and Drug Design, 2021
Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation
Sahaya Nadar, T. Khan
semanticscholar   +1 more source

Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Biologically Active Agents.

Current Medicinal Chemistry, 2020
Pyridine and pyrimidine derivatives have received great interest in recent pharmacological research, being effective in the treatment of various malignancies, such as myeloid leukemia, breast cancer and idiopathic pulmonary fibrosis.
M. Chiacchio, D. Iannazzo, R. Romeo, S. Giofrè, L. Legnani   +4 more
semanticscholar   +1 more source

Recent Development of Pyrimidine‐Containing Antimicrobial Agents

ChemMedChem, 2020
Multidrug‐resistant bacterial infections have become an important cause of clinical death in the twenty‐first century. Much effort has been made to overcome this challenge.
Jianxing Zhuang, Shutao Ma
semanticscholar   +1 more source

A Review on Synthesis, Anticancer and Antiviral Potentials of Pyrimidine Derivatives

Current Bioactive Compounds, 2019
Pyrimidine is the six membered heterocyclic aromatic compound similar to benzene and pyridine containing two nitrogen atoms at 1st and 3rd positions.
Sanjiv Kumar, A. Deep, B. Narasimhan
semanticscholar   +1 more source

De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence

Nature Cell Biology, 2023
Chuanzhen Yang, Yiliang Zhao, Liao Wang, Zihao Guo, Ling-di Ma, Ronghui Yang, Ying Wu, Xuexue Li, J. Niu, Q. Chu, Yanxia Fu, Binghui Li   +11 more
semanticscholar   +1 more source

Pyrimidine and fused pyrimidine derivatives as promising protein kinase inhibitors for cancer treatment

, 2020
Khaled R. A. Abdellatif, R. Bakr
semanticscholar   +1 more source

Adsorption Behavior of Glucosamine-Based, Pyrimidine-Fused Heterocycles as Green Corrosion Inhibitors for Mild Steel: Experimental and Theoretical Studies

, 2016
C. Verma, L. Olasunkanmi, E. Ebenso, M. Quraishi, I. Obot   +4 more
semanticscholar   +1 more source