Results 271 to 280 of about 290,598 (376)

Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors. [PDF]

open access: yes, 1993
Duquesnoy, RJ   +6 more
core  

Evaluation of the Antifungal Properties of Azomethine‐Pyrazole Derivatives from a Structural Perspective

open access: yesChemistryOpen, EarlyView.
A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo   +8 more
wiley   +1 more source

A cytidine deaminase-like protein modulates pyrimidine nucleotide homeostasis in Trypanosoma brucei. [PDF]

open access: yesSci Rep
Moro-Bulnes A   +9 more
europepmc   +1 more source

Gas Chromatography‐Mass Spectrometry Analysis, Genoprotective, and Antioxidant Potential of Curio radicans (L. f.) P.V. Heath

open access: yesChemistryOpen, EarlyView.
The ethyl acetate extract of Curio radicans is found to contain a higher proportion of bioactive compounds (55% vs 30% in the ethanolic extract) by gas chromatography‐mass spectrometry, and it exhibits stronger antioxidant activity in the DPPH assay (75% vs 65% inhibition) as well as clear genoprotective effects against H2O2‐induced DNA damage ...
Muhammad Naseer   +6 more
wiley   +1 more source

Ionization of DNA Nucleotides in Explicit Solution. [PDF]

open access: yesMolecules
Bai J, Zhang Y, Yin S, Che L, Yang S.
europepmc   +1 more source

Efficient Synthesis of 1‐Chloroimidazo[1,2‐a:4,5‐c']dipyridines, Versatile Synthons for Position‐1 Functionalisation with Various Reagents

open access: yesChemistryOpen, EarlyView.
Imidazo[1,2‐a:4,5‐c']dipyridines are remarkable skeletons in the field of medicinal chemistry. This article presents the synthesis of 1‐chloroimidazo[1,2‐a:4,5‐c']dipyridines, versatile synthons to functionalize at position‐1. Several examples of further reactions are presented, including Suzuki–Miyaura and Sonogashira cross‐couplings, nucleophilic ...
Romain Dussart   +3 more
wiley   +1 more source

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