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1992
This chapter explores pyrimidines. Formal replacement of a CH unit in pyridine by a nitrogen atom leads to the series of three possible diazines: pyridazine, pyrimidine, and pyrazine. Like pyridine, they are fully aromatic heterocycles. The effect of an additional nitrogen atom as compared to pyridine accentuates the essential features of pyridine ...
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This chapter explores pyrimidines. Formal replacement of a CH unit in pyridine by a nitrogen atom leads to the series of three possible diazines: pyridazine, pyrimidine, and pyrazine. Like pyridine, they are fully aromatic heterocycles. The effect of an additional nitrogen atom as compared to pyridine accentuates the essential features of pyridine ...
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Pyrimidines. VIII. Pyrimidine Derivatives of Thioguanine
Journal of Medicinal and Pharmaceutical Chemistry, 1962H C, KOPPEL +3 more
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A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
Cancer Cell, 2022Sharmistha Pal +2 more
exaly
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
Cancer Cell, 2022Michael M Levitt, Yi Xiao, Bofu Huang
exaly