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Formation of Cyclobutane Pyrimidine Dimers after UVA Exposure (Dark-CPDs) Is Inhibited by an Hydrophilic Extract of Polypodium leucotomos [PDF]

open access: yesAntioxidants, 2021
Exposure to sun and especially to ultraviolet radiation (UVR) exerts well known detrimental effects on skin which are implicated in malignancy. UVR induces production of cyclobutane pyrimidine dimers (CPDs), immediately during exposure and even hours ...
Mikel Portillo-Esnaola   +6 more
doaj   +2 more sources

All You Need Is Light. Photorepair of UV-Induced Pyrimidine Dimers. [PDF]

open access: goldGenes (Basel), 2020
Banaś AK   +5 more
europepmc   +3 more sources

The compost metagenome as a source of T4 bacteriophage pyrimidine dimer glycosylase homologues [PDF]

open access: yesE3S Web of Conferences, 2021
Compost is a promising source of thermotolerant enzymes for their application in biotechnology. Homologues of bacteriophage T4 DNA glycosylase can find their application in pharmaceuticals and perfumery.
Karmanova Alexandra N.   +2 more
doaj   +1 more source

Events associated with DNA replication disruption are not observed in hydrogen peroxide-treated Escherichia coli

open access: yesG3: Genes, Genomes, Genetics, 2021
UV irradiation induces pyrimidine dimers that block polymerases and disrupt the replisome.
Chettar A Hoff   +5 more
doaj   +1 more source

Recombination between homologous chromosomes induced by unrepaired UV-generated DNA damage requires Mus81p and is suppressed by Mms2p. [PDF]

open access: yesPLoS Genetics, 2015
DNA lesions caused by UV radiation are highly recombinogenic. In wild-type cells, the recombinogenic effect of UV partially reflects the processing of UV-induced pyrimidine dimers into DNA gaps or breaks by the enzymes of the nucleotide excision repair ...
Yi Yin, Thomas D Petes
doaj   +1 more source

7-Chloro-3-(4-methylbenzenesulfonyl)pyrrolo[1,2-c]pyrimidine

open access: yesIUCrData, 2020
In the title compound, C14H11ClN2O2S, the dihedral angle between the pyrrolo[1,2-c]pyrimidine ring system (r.m.s. deviation = 0.008 Å) and the benzene ring is 80.2 (9)°.
Easha Narayan   +4 more
doaj   +1 more source

2-Chloropyrimidin-4-amine

open access: yesActa Crystallographica Section E, 2012
In the title pyrimidine derivative, C4H4ClN3, the 2-chloro and 4-amino substituents almost lie in the mean plane of the pyrimidine ring, with deviations of 0.003 (1) Å for the Cl atom, and 0.020 (1) & ...
Gerard A. van Albada   +3 more
doaj   +1 more source

6-Chloro-N4,N4-dimethylpyrimidine-2,4-diamine

open access: yesActa Crystallographica Section E, 2012
The asymmetric unit of the title compound, C6H9ClN4, contains four independent molecules (A, B, C and D). Their main difference is the torsion angles, ranging from 1.6 (5) to 5.9 (5)°, between the methyl group and the ...
Bin Sun   +3 more
doaj   +1 more source

Transcription-Coupled Repair in Plants

open access: yesFrontiers in Plant Science, 2012
UV-induced pyrimidine dimers block the progression of both DNA and RNA polymerases. In order to reduce the disruptive effect of these lesions on gene expression, bacteria, yeasts, and animals preferentially repair the transcribed strand of actively ...
Ana Lena Fidantsef, Anne Bagg Britt
doaj   +1 more source

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