Results 31 to 40 of about 16,097 (238)

tert-Butyl N-{4-methyl-3-[4-(3-pyridyl)pyrimidin-2-yloxy]phenyl}carbamate

open access: yesActa Crystallographica Section E, 2009
In the molecule of the title compound, C21H22N4O3, the pyrimidine ring is oriented at dihedral angles of 0.51 (3) and 50.76 (3)° to the pyridine and benzene rings, respectively. In the crystal structure, intermolecular N&#
Shi-Gui Tang, Jian-Qiang Wang, Cheng Guo
doaj   +1 more source

Methyl 4-[N-(5-bromopyrimidin-2-yl)carbamoyl]benzoate

open access: yesActa Crystallographica Section E, 2012
In the title compound, C13H10BrN3O3, the pyrimidine and benzene rings are twisted with an interplanar angle of 58.4 (1)°. The secondary amide group adopts a cis conformation with an H—N—C—O torsion angle ...
Hui-Ling Hu   +3 more
doaj   +1 more source

N-Butyl-4-methyl-6-phenylpyrimidin-2-amine

open access: yesActa Crystallographica Section E, 2010
In the title compound, C15H19N3, the pyrimidine ring is approximately planar [maximum deviation = 0.007 (1) Å] and forms a dihedral angle of 3.15 (6)° with the benzene ring.
Hoong-Kun Fun   +3 more
doaj   +1 more source

Recognition in action: flipping pyrimidine dimers [PDF]

open access: yesJournal of Molecular Recognition, 2005
DNA bases are normally sheltered within a double helix, but enzymes that modify and repair DNA gain access by flipping individual bases out of the double helix.
openaire   +2 more sources

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate

open access: yesActa Crystallographica Section E, 2011
In the title compound, C24H22N2O6S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7 ...
H. Nagarajaiah, Noor Shahina Begum
doaj   +1 more source

Unlocking Catalyst Activation as a Critical Bottleneck in Cross‐Coupling Reactions: Room‐Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1‐MeNAP)TFA]2 Precatalysts

open access: yesAngewandte Chemie International Edition, EarlyView.
In many Pd‐catalyzed cross‐couplings, catalyst performance has been found to be limited by catalyst activation. Methylnaphthyl (MeNAP) palladium trifluoroacetate dimers are presented as easy‐to‐store and easy‐to‐handle precursors, which rapidly activate under reaction conditions, even when only weakly coordinating, non‐reducing nucleophiles are present.
Sourav Manna   +6 more
wiley   +1 more source

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

open access: yes, 1968
Within 12–24 hr after human cells were irradiated with ultraviolet light, approximately 50% of the ultraviolet-induced pyrimidine dimers were lost from the DNA.
Carrier, William L.   +2 more
core   +1 more source

Studies on the Mechanism of the Photosensitized Dimerization of Pyrimidines

open access: yesZeitschrift für Naturforschung B, 1972
Thymine-2-14C was irradiated with UV light (>300 nm) in water solutions in the presence of different sensitizers. Pyrimidines upon irradiation with wavelengths of 300—320 nm in the presence of some ketones as sensitizers, yield cyclobutyl pyrimidine dimers.
A, Kornhauser, M A, Pathak
openaire   +2 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

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