Results 51 to 60 of about 16,097 (238)
4-{4-Methyl-2-[(methyl)(2-methylphenyl)amino]-1,3-thiazol-5-yl}-N-(3-methylphenyl)pyrimidin-2-amine
Acta Crystallographica Section E, 2011 In the title compound, C23H23N5S, the thiazole ring and pyrimidine ring are almost coplanar, making a dihedral angle of 4.02 (9)°.
Hai-Bo Shi +3 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.The synergic action of ascorbic acid and NHC^N ligands enables Au(I) oxidation with electron‐rich aryldiazonium salts. ABSTRACT The synergistic action of ascorbic acid and NHC^N ligands enables the challenging oxidation of Au(I) with electron‐rich aryldiazonium salts in the absence of a cocatalyst and/or irradiation. EPR, NMR, and x‐ray analyses reveal
Paula G. Cárdenas‐Cárdenas +7 more
wiley +1 more source
Variations in Excision Repair of UVB-Induced Pyrimidine Dimers in DNA of Human Skin in Situ
, 1988 The excision repair kinetics of UVB (280–320 nm)*-induced pyrimidine dimers in DNA of human skin in situ was determined for seventeen volunteers using a dimer-specific endonuclease from Micrococcus luteus in conjunction with agarose gel electrophoresis ...
Freeman, Steven E.
core +1 more source
Acta Crystallographica Section E, 2011 In the title compound, C22H19Cl2N5S, the thiazole and pyrimidine rings are almost co-planar, making a dihedral angle of 6.48 (7)°.
Hai-Bo Li, Hai-Bo Shi, Wei-Xiao Hu
doaj +1 more source
Effects of DNA looping on pyrimidine dimer formation [PDF]
Nucleic Acids Research, 1992 We have assessed the effects of DNA curvature on pyrimidine dimer (PD) formation by examining the pattern of PD formation in DNA held in a loop by lambda repressor. The loop region was composed of diverse DNA sequences such that potential PD sites occurred throughout the loop.
J R, Pehrson, L H, Cohen
openaire +2 more sources
Journal of Applied Toxicology, EarlyView.ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü +3 more
wiley +1 more source
Induction of Pyrimidine Dimers in Epidermal DNA of Hairless Mice by UVB: An Action Spectrum
, 1983 An action spectrum for the induction of pyrimidine dimers in the epidermis of hairless mice was determined between 288 and 307 nm. The presence of pyrimidine dimers in tritium-labeled DNA extracted from exposed SKH:hairless-1 mouse skin was determined ...
Ley, Ronald D. +2 more
core +1 more source
Journal of the Chinese Chemical Society, EarlyView.Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley +1 more source
UV-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells
, 1986 We used a simian virus 40-based shuttle vector plasmid, pZ189, to determine the role of pyrimidine cyclobutane dimers in UV light-induced mutagenesis in monkey cells. The vector DNA was UV irradiated and then introduced into monkey cells by transfection.
Munson, P. J. +5 more
core +1 more source
Ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate monohydrate
Acta Crystallographica Section E, 2008 There are three formula units in the asymmetric unit of the title compound, C14H16N2O4·H2O. Molecules are linked by N—H...O hydrogen bonds into dimers with the common R22(8) graph-set motif.
T. N. Guru Row +4 more
doaj +1 more source