Results 41 to 50 of about 16,097 (238)

1,3-Bis(4-methylbenzyl)pyrimidine-2,4(1H,3H)-dione

Acta Crystallographica Section E, 2010
In the title molecule, C20H20N2O2, the central pyrimidine ring forms dihedral angles of 71.9 (1) and 69.8 (1)° with the two benzene rings.
Gong-Chun Li, Xiao-Ping Song, Li-Ke Zhang, Jiao-Jiao Cui, Feng-Ling Yang   +4 more
doaj   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Formation and repair of psoralen-DNA adducts and pyrimidine dimers in human DNA and chromatin. [PDF]

, 1985
DNA damage and repair in human cells exposed to ultraviolet light (254 nm) or to psoralen derivatives plus 360 nm light were compared by means of a variety of analytic techniques.
S Killpack, Cleaver, JE, Gruenert, DC, J E Cleaver, Killpack, S, D C Gruenert   +5 more
core   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

2-Dicyclohexylamino-3-phenyl-5,6-dihydro-8H-thiopyrano[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(3H)-one

Acta Crystallographica Section E, 2011
In the title compound, C27H33N3OS2, the dihedral angle between the two fused rings of the thieno[3,2-d]pyrimidine system is 3.73 (9)°. The phenyl ring is twisted with respect to the pyrimidine ring [dihedral angle = 71.60 (10)
Xizhen Liang, Yueming Zhou
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

5-Propyl-6-(p-tolylsulfanyl)pyrimidine-2,4(1H,3H)-dione

Acta Crystallographica Section E, 2014
In the title pymiridine-2,4-dione derivative, C14H16N2O2S, the dihedral angle between the six-membered rings is 66.69 (10)°. The molecule is twisted about the Cp—S (p = pyrimidine) bond, with a C—S—C—N torsion angle of −19.57 (16)°.
Fatmah A. M. Al-Omary, Hazem A. Ghabbour, Ali A. El-Emam, C. S. Chidan Kumar, Hoong-Kun Fun   +4 more
doaj   +1 more source

The Asymmetric Self‐Replicative Alkylation of N‐Arylaldimines Using Organolithium Reagents

Chemistry – A European Journal, EarlyView.
Here, we report a new asymmetric autoinductive reaction; the addition of nBuLi to N‐arylaldimines to form chiral lithium amides. The reaction proceeds with full conversion and complete transfer of chirality, representing the first example of an asymmetric autoinductive reaction with organolithium reagents.
Anka Hagelschuer, Paco Visser, Ben L. Feringa   +2 more
wiley   +1 more source

Excision Repair of UV-induced Pyrimidine Dimers in Human Skin in Vivo

, 1981
The induction and loss of pyrimidine dimers in human skin in vivo was determined using UV endonuclease, alkaline sucrose sedimentation, and the fluorescent detection of nonradiolabeled DNA.
Whetstone, James W., Slazinski, Leonard, D'Ambrosio, Steven M., Lowney, Edmund   +3 more
core   +1 more source

Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair

Nature Communications, 2017
Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.
Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa   +14 more
doaj   +1 more source