Results 11 to 20 of about 16,097 (238)

Pyrimidine Dimers in the DNA of Paramecium aurelia

open access: yesBiophysical Journal, 1968
The production and fate of thymine-containing pyrimidine dimers in Paramecium aurelia DNA was investigated in three experimental series: production of dimers by UV irradiation, fate of dimers in the dark, and "loss of photoreactivability of dimers." It is shown that cyclobutyl dimers are made by UV irradiation of Paramecium DNA in vivo, that because of
Sutherland, B.M.   +2 more
openaire   +3 more sources

4-Chloro-1H-pyrrolo[2,3-d]pyrimidine

open access: yesActa Crystallographica Section E, 2012
The title compound, C6H4ClN3, is essentially planar with the pyrrole and pyrimidine rings inclined to one another by 0.79 (15)°. In the crystal, molecules are connected via pairs of N—H...N hydrogen bonds, forming inversion ...
Su-Lan Dong, Xiaochun Cheng
doaj   +2 more sources

UV-Driven Self-Repair of Cyclobutane Pyrimidine Dimers in RNA

open access: yes, 2023
Nucleic acids can be damaged by ultraviolet (UV) irradiation, forming structural photolesions such as cyclobutane-pyrimidine-dimers (CPD). In modern organisms, sophisticated enzymes repair CPD lesions in DNA, but to our knowledge, no RNA-specific enzymes
Corinna, Kufner   +5 more
core   +1 more source

6-Chloro-N4,N4-dimethylpyrimidine-2,4-diamine

open access: yesActa Crystallographica Section E, 2012
The asymmetric unit of the title compound, C6H9ClN4, contains four independent molecules (A, B, C and D). Their main difference is the torsion angles, ranging from 1.6 (5) to 5.9 (5)°, between the methyl group and the ...
Bin Sun   +3 more
doaj   +1 more source

Transcription-Coupled Repair in Plants

open access: yesFrontiers in Plant Science, 2012
UV-induced pyrimidine dimers block the progression of both DNA and RNA polymerases. In order to reduce the disruptive effect of these lesions on gene expression, bacteria, yeasts, and animals preferentially repair the transcribed strand of actively ...
Ana Lena Fidantsef, Anne Bagg Britt
doaj   +1 more source

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(naphthalen-1-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The title compounds, C16H15N5OS, (I), and C12H12FN5OS, (II), are [(diaminopyrimidine)sulfanyl]acetamide derivatives. In (I), the pyrimidine ring is inclined to the naphthalene ring system by 55.5 (1)°, while in (II), the pyrimidine ring is inclined to ...
S. Subasri   +5 more
doaj   +1 more source

Crystal structure of (2-methyl-4-phenyl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-3-yl)(phenyl)methanone

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C24H18N2OS, the pyrimidine ring has a flat envelope conformation with the methine C atom as the flap. The attached phenyl and benzoyl rings are inclined to the mean plane of the pyrimidine ring by 84.87 (8) and 75.33 (9 ...
T. Sankar   +3 more
doaj   +1 more source

4-Methyl-6-(piperidin-1-yl)pyrimidin-2-amine

open access: yesActa Crystallographica Section E, 2013
The title compound, C10H16N4, crystalizes with two molecules (A and B) in the asymmetric unit in which the dihedral angles between the piperidine and pyrimidine rings are 47.5 (1) and 10.3 (1)°. The four C atoms of the pyrimidine ring in
S. Sreenivasa   +5 more
doaj   +1 more source

UV micro-irradiation of the Chinese hamster cell nucleus and caffeine post-treatment immunocytochemical localization of DNA photolesions in cells with partial and generalized chromosome shattering [PDF]

open access: yes, 1983
UV micro-irradiation of a small part of the Chinese hamster nucleus and caffeine post-incubation often results in shattered chromosomes at the first post-irradiation mitosis.
Cornelis, Jan J.   +8 more
core   +1 more source

Methyl 2-[2-(benzyloxycarbonylamino)propan-2-yl]-5-hydroxy-6-methoxypyrimidine-4-carboxylate

open access: yesActa Crystallographica Section E, 2011
In the title compound, C18H21N3O6, a pyrimidine derivative, the dihedral angle between the benzene and pyrimidine rings is 52.26 (12)°.
Hoong-Kun Fun   +4 more
doaj   +1 more source

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